| 益气养阴方联合蚓激酶胶囊防治IgA肾病气阴两虚型临床观察 |
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| 引用本文： | 金周慧,陈月琴,彭文,姚卫国.益气养阴方联合蚓激酶胶囊防治IgA肾病气阴两虚型临床观察[J].中华中医药学刊,2011(12):2822-2824. |
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| 作者姓名： | 金周慧 陈月琴 彭文 姚卫国 |
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| 作者单位： | 上海市普陀区利群医院中医科;上海中医药大学附属普陀医院肾脏科; |
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| 摘 要： | 目的:观察益气养阴方联合蚓激酶胶囊治疗IgA肾病气阴两虚型的临床疗效。方法:经肾穿刺活检确诊IgA肾病和中医辨证为气阴两虚型患者50例,对照组(n=25例)用益气养阴方,蚓激酶组(n=25例)用益气养阴方联合蚓激酶胶囊,均治疗6个月。观察临床症状和血液流变学、纤维蛋白原、D-二聚体、u-PA、PAI-1,血清肌酐(Scr),尿红细胞计数、24h尿蛋白量治疗前后的变化情况。结果:两组患者血浆黏度、血小板聚集率、纤维蛋白原、血清肌酐、尿红细胞计数、24h尿蛋白量与治疗前比较均有统计学差异(P<0.05或P<0.01),且两组间临床症状积分、血液流变学、纤维蛋白原的结果比较有统计学差异(P<0.05),蚓激酶组总有效率达96%。结论:益气养阴方联合蚓激酶胶囊能显著改善IgA肾病患者血液流变、降低血尿、蛋白尿,缓解临床症状,对IgA肾病有较好地防治作用。
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| 关 键 词： | 蚓激酶 IgA肾病 中医 益气养阴方 |
Effect of Yiqi Yangyin Decoction United Lumbrokinase Capsule with Qi and Yin Deficiency Type of IgA Nephropathy |
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| JIN Zhou-hui,CHEN Yue-qing,PENG Wen,YAO Wei-guo.Effect of Yiqi Yangyin Decoction United Lumbrokinase Capsule with Qi and Yin Deficiency Type of IgA Nephropathy[J].Chinese Archives of Traditional Chinese Medicine,2011(12):2822-2824. |
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| Authors: | JIN Zhou-hui CHEN Yue-qing PENG Wen YAO Wei-guo |
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| Institution: | JIN Zhou-hui1,CHEN Yue-qing1,PENG Wen2,YAO Wei-guo2(1.Shanghai Liqun Hospital,Putuo Distract,Shanghai 200333,China,2.Shanghai University of TCM affiliated Putuo Hospital,Department of Nephropathy Shanghai 200062,China) |
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| Abstract: | Objective:To observe the effect of Yiqi Yangyin Decoction united lumbrokinase capsules on patients with Qi and Yin Deficiency type of IgA nephropathy.Methods:The renal biopsy confirmed 50 cases of IgA nephropathy and traditional Chinese physician identified the type of qi and yin deficiency.They were divided into control group(n= 25 patients),which were treated by Yiqi Yangyin Decoction,and lumbrokinase group(n= 25 patients),which were treated by Yiqi Yangyin Decoction united lumbrokinase capsules.All were ... |
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| Keywords: | lumbrokinase IgA nephropathy Traditional Chinese Medicine(TCM) Yiqi Yangyin Decoction |
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