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活血益气法对气滞血瘀证2型糖尿病大鼠治疗的实验研究
引用本文:陈嘉斌,柴可夫,张副兴,吕帅洁,郑杨. 活血益气法对气滞血瘀证2型糖尿病大鼠治疗的实验研究[J]. 中华中医药学刊, 2011, 0(10): 2228-2230
作者姓名:陈嘉斌  柴可夫  张副兴  吕帅洁  郑杨
作者单位:浙江中医药大学;
基金项目:浙江省教育厅浙江省大学生科技创新活动计划(新苗人才计划)立项资助项目(67401129)
摘    要:目的:研究活血益气法对于气滞血瘀证型2型糖尿病大鼠模型的治疗作用。方法:对大鼠用针刺激[1]及高脂高糖饮食[2]建立气滞血瘀证型。后给予大鼠日照并灌胃脂肪乳10日后尾静脉一次性注射四氧嘧啶(80mg/kg)建立2型糖尿病模型。采用血府逐瘀汤加生黄芪怀山药进行治疗并检测指标。结果:通过血液流变学指标,血糖等客观指标分析,模型建立可靠,气滞血瘀证型2型糖尿病大鼠各指标明显好转。结论:使用针刺及高脂喂食建立模型可为将来2型糖尿病中医研究提供实验基础,活血益气法治疗气滞血瘀证2型糖尿病具有较好的疗效,但用药需谨慎配伍。

关 键 词:活血益气法  气滞血瘀证型  动物模型  四氧嘧啶

The Experiment Research on Qi Stasis Plus Blood Stasis Diabetic Rat Models with Active-blood Soup and yiqi-vein's Method
CHEN Jia-bin,CHAI Ke-fu,ZHANG Fu-xing,LV Shuai-jie,ZHENG Yang,advisor: CHAI Ke-fu. The Experiment Research on Qi Stasis Plus Blood Stasis Diabetic Rat Models with Active-blood Soup and yiqi-vein's Method[J]. Chinese Archives of Traditional Chinese Medicine, 2011, 0(10): 2228-2230
Authors:CHEN Jia-bin  CHAI Ke-fu  ZHANG Fu-xing  LV Shuai-jie  ZHENG Yang  advisor: CHAI Ke-fu
Affiliation:CHEN Jia-bin,CHAI Ke-fu,ZHANG Fu-xing,LV Shuai-jie,ZHENG Yang,advisor: CHAI Ke-fu(Zhejiang Traditional Chinese Medical University,Hangzhou 310000,Zhejiang,China)
Abstract:Objective: To study the effect on Qi stasis plus blood stasis diabetic rat models by Active-blood soup and yiqi-vein's method.Methods:The Qi stasis plus blood stasis diabetic rat models were made by electroacupuncture stimulation and high-sugar-fat-diet.Then give them Fat Emulsion and sunlight for 10 days before injecting one-off Alloxan monohydrate on the vein of tail.Give the treatment with Active-blood soup and yiqi-vein's method and record the index.Results:According to the analysis of hemorheology indi...
Keywords:Active-blood soup and yiqi-vein's method  Qi stasis plus blood stasis  rat models  Alloxan monohydrate  
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