| 滋阴健脑片早期干预脑梗死后认知功能损害的临床与实验研究 |
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| 引用本文： | 宁为民,缪晓路,莫换好,陈敬毅.滋阴健脑片早期干预脑梗死后认知功能损害的临床与实验研究[J].中华中医药学刊,2011(8):1861-1863. |
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| 作者姓名： | 宁为民 缪晓路 莫换好 陈敬毅 |
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| 作者单位： | 东莞市中医院; |
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| 基金项目： | 东莞市科技局资助项目(2008105150032) |
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| 摘 要： | 目的:探讨滋阴健脑片早期干预脑梗死后认知功能损害的疗效。方法:临床研究选择57例脑梗死后认知功能轻度损害的肾精亏虚证患者随机分成试验组29例和对照组28例,对照组予尼莫地平片,试验组在对照组的基础上予滋阴健脑片,连续2个月,观察对中医证候、认知功能及神经功能缺损的影响;实验研究选择27只实验大鼠建立血管性痴呆的动物模型,并随机分为模型组9例、尼莫地平片组9例及滋阴健脑片组9例,灌胃给药30天,同时设正常对照组9例,观察对学习记忆能力及氧自由基的影响。结果:2个月后观察,试验组在中医证候积分、简易精神状态检查表(MMSE)评分、临床神经功能缺损程度评分方面较对照组有改善作用(P≦0.05);实验研究证实滋阴健脑片不仅可以减缓学习功能的衰退,而且可以提高超氧化物歧化酶活力及降低丙二醛活性。结论:滋阴健脑片对脑梗死后认知功能损害肾精亏虚证有早期干预作用,联合用药有增益效应。各自
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| 关 键 词： | 滋阴健脑片 脑梗死后认知功能损害 早期干预 |
The Clinical And Experimental Research On Ziyinjiannao Tablet Early Treating The Cognition Impairment After Cerebral Infarction |
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| NING Wei-min,MIAO Xiao-lu,MO Huan-hao,CHEN Jin-yi.The Clinical And Experimental Research On Ziyinjiannao Tablet Early Treating The Cognition Impairment After Cerebral Infarction[J].Chinese Archives of Traditional Chinese Medicine,2011(8):1861-1863. |
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| Authors: | NING Wei-min MIAO Xiao-lu MO Huan-hao CHEN Jin-yi |
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| Institution: | NING Wei-min,MIAO Xiao-lu,MO Huan-hao,CHEN Jin-yi(Dongguan Hospital of Chinese traditional medicine,Guangdong Dongguan,523006) |
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| Abstract: | Objective: to study on Ziyinjiannao Tablet early treating the cognition impairment after cerebral infarction.Method: The 57 patients of mild cognitive impairment after cerebral infarction of the kidney essence deficiency were studied in the clinical research,which were divided into the experiment group(29 patients) and the control group(28 patients) randomly.The control group was taken Nimodipine tablet.And the experiment group was taken Ziyinjiannao tablet based on treatment of the control group.After two ... |
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| Keywords: | Ziyinjiannao tablet cognitive impairment after cerebral infarction early treatment |
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