Synthesis and Pharmacological Activity of N-[β-(<Emphasis Type="Italic">para</Emphasis>-substituted benzoyl)ethyl]isoleucine and -Methionine |
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| Authors: | A G Agababyan A Y Isakhanyan O A Papoyan A E Tumadzhyan A S Balasanyan G A Gevorgyan |
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| Institution: | (1) Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of Armenia, Yerevan, Armenia |
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| Abstract: | A series of N-β-(p-substituted benzoyl)ethyl]-isoleucine and -methionine derivatives have been synthesized via the alkylation of amino acids
with p-substituted β-diethylaminopropiophenone hydrochlorides. Some of the synthesized compounds possess significant antiinflammatory
activity.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 39, No. 7, pp. 26 – 27, July, 2005. |
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