| 雪域肝胆康胶囊对小鼠实验性肝损伤及胆汁的影响 |
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| 引用本文： | 张涓,刘邦民,王勇,顾健,周春阳,黄国钧.雪域肝胆康胶囊对小鼠实验性肝损伤及胆汁的影响[J].华西药学杂志,2007,22(2):163-165. |
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| 作者姓名： | 张涓 刘邦民 王勇 顾健 周春阳 黄国钧 |
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| 作者单位： | 成都中医药大学,四川,成都,610075;陕西中医学院,陕西,咸阳,712083;成都中医药大学,四川,成都,610075;西南民族大学,四川,成都,610041 |
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| 摘 要： | 目的 研究藏药雪域肝胆康胶囊(XYGD)的保肝利胆作用.方法 以CCl4制作动物急性肝损伤模型,测定血清ALT、AST、TBIL的含量,观察XYCD对动物急性肝损伤的影响;采用麻醉大鼠行胆汁引流术,测定正常大鼠的胆汁分泌量及胆汁成分.结果 雪域肝胆康胶囊能明显降低CCl4急性肝损伤动物血清ALT、AST水平;使正常大鼠的胆汁流量明显增加,降低胆汁中胆固醇的浓度.结论 XYGD有明显保肝、利胆作用.
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| 关 键 词： | 雪域肝胆康胶囊 保肝 利胆 肝损伤 |
| 文章编号： | 1006-0103（2007）02-0163-03 |
| 修稿时间： | 2006-02 |
Effects of Tibetan medicine Xueyu Gandankang capsules on liver protection and bile secretion |
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| ZHANG Juan,LIU Bang-min,WANG Yong,GU Jian,ZHOU Chun-yang,HUANG Guo-jun.Effects of Tibetan medicine Xueyu Gandankang capsules on liver protection and bile secretion[J].West China Journal of Pharmaceutical Sciences,2007,22(2):163-165. |
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| Authors: | ZHANG Juan LIU Bang-min WANG Yong GU Jian ZHOU Chun-yang HUANG Guo-jun |
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| Institution: | 1. Chengdu University of Traditional Chinese Medicine, Chengdu 611731, China; 2. Southwest University for Nationalities, Chengdu 610041, China; 3. Shaanxi College of Traditional Chinese Medicine, Xianyang 712083, China |
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| Abstract: | OBJECTIVE To study the liver - protection and promoting bile secretion of Tibetan medicine formula Xueyu Gandankang capsules. METHODS Tibetan medicine formula Xueyu Gandankang capsules was administrated to the mice with liver injury induced by CCl4. ALT, AST and TBIL levels in serum were examined . The bile flow rate and the concentration of rats administrated with Tibetan medicine formula Xueyu Gandankang capsules were estimated. RESULTS Tibetan medicine formula Xueyu Gandankang capsules could decrease the ALT,AST in the serum of mice treated with CCl4, promote the secretion of bile and decrease the biliary cholesterol level. CONCLUSION Tibetan medicine formula Xueyu Gandankang capsules exhibited significant liver protection and promoting of bile secretion. |
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| Keywords: | Tibetan medicine formula Xueyu Gandankang capsules Liver - protection Promoting bile secretion |
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