Human myosin heavy chain genes assigned to chromosome 17 using a human cDNA clone as probe |
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| Authors: | Y. H. EDWARDS,M. PARKAR,S. POVEY,L. F. WEST,J. M. PARRINGTON,E. SOLOMON&dagger |
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| Affiliation: | *M.R.C. Human Biochemical Genetics Unit, Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE;†Imperial Cancer Research Fund Laboratories, PO Box 123, Lincoln's Inn Fields, London WC2A 3PX |
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| Abstract: | A cDNA clone complementary to the mRNA encoding human myosin heavy chain has been isolated from a human fetal skeletal muscle cDNA library. A 600 base pair fragment of the inserted human cDNA has been used as probe in the Southern analysis of DNA from panels of rat/human and mouse/human somatic cell hybrids. All the sequences detected by this probe have been mapped to chromosome 17 in the region 17pter → 17p11. There was no evidence for MHC sequences on any other chromosome. |
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