高良姜化学成分及药理活性的研究

对近年来有关高良姜化学成分和药理作用的研究进行介绍，高良姜为一种常用中药，其化学成分主要包括挥发油类、黄酮类、二芳基庚烷类、苯丙素类、糖苷类等。药理学研究表明高良姜具有抗菌作用、抗病毒作用、抗肿瘤作用、抗氧化作用、抗胃肠道出血作用、抗溃疡作用和胃黏膜保护作用等。无论是高良姜粗提物还是其中所包含的具体的化学成分都表现出较好的药理活性，尤其是高良姜中的二芳基庚烷类化合物和黄酮类化合物的药理活性的研究比较广泛，他们在抗肿瘤、抗氧化以及与其他药物联合应用抗多重耐药菌株方面的应用日益受到人们的关注。今后在探讨高良姜中的二芳基庚烷类化合物和黄酮类化合物的药理活性时，更应该注重同类成分之间的相互比较，寻找药理活性必须基团，明确构效关系，深入探讨作用机制，进一步促进高良姜药材的综合开发利用。

Advances in Studies on Chemical Constituents in Alpiniae Officinarum Rhizoma and their Pharmacological Activities

Alpiniae officinarum rhizoma has been used as a folk medicine and contains essential oil, flavonoids, diarylheptanoids, phenylpropanoids, glycosides and other constituents. According to recent pharmacological research reports, this medicine has various pharmacological activities including antimicrobial activity, antiviral activity, antitumous activity, antioxidant activity, gastric ulcer therapy and as a hemostat in the treatment of gastrointestinal hemorrhages. For further exploitation and sustainable utilization of this folk medicine, the information about the chemical constituents and pharmacological activities of the rhizoma of Alpinia officinarum that have appeared in recent years were summarized.