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难治性癫痫患者的苯妥英钠血药浓度监测及用药分析
引用本文:夏运岳,金卫坤,陈幼亭. 难治性癫痫患者的苯妥英钠血药浓度监测及用药分析[J]. 中国临床药学杂志, 1996, 0(3)
作者姓名:夏运岳  金卫坤  陈幼亭
作者单位:苏州医学院附属一院临床药理研究室!215006
摘    要:本文对38例服用苯妥英钠的难治性癫痫患者进行血药浓度监测和用药分析.结果38例中,中毒人数为21例,用药不足人数7例.提示难治性癫痫患者与苯妥英钠的用药水平有关,临床应用苯妥英钠应个体化,每位患者的治疗剂量不能只凭经验用药,必须进行血药浓度监测.

关 键 词:苯妥英钠  血药浓度监测  用药分析

SERUM PHENYTOIN SODIUM CONCENTRATION MONITORED AND ANALYSIS OF APPLICATION DRUG IN REFRACTORY EPILEPTIC PATIENTS
XIA Yun-yue JIN Wei-kun CHEN You-ting. SERUM PHENYTOIN SODIUM CONCENTRATION MONITORED AND ANALYSIS OF APPLICATION DRUG IN REFRACTORY EPILEPTIC PATIENTS[J]. Chinese Journal of Clinical Pharmacy, 1996, 0(3)
Authors:XIA Yun-yue JIN Wei-kun CHEN You-ting
Abstract:38 refractory epileptic patients were monitored with serum phenytoin sodium concentration and analysed application drug. The results showed the people of intoxication was 21. the people of deficiency drug was 7 in 38 patients. The refractory epileptic patients had relation with level of phenytoin sodium concentration. The drug dosage could not decided only by clinical experiences. Drug therapy should be adjusted individually based on the serum concentration.
Keywords:PHT  phenytoin sodium  monitoring of therapeutic drugs  
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