| 神经胶质瘤基因治疗的研究进展 |
| |
| 引用本文： | 赵亮,肖红,冯芳.神经胶质瘤基因治疗的研究进展[J].医学综述,2007,13(7):492-494. |
| |
| 作者姓名： | 赵亮 肖红 冯芳 |
| |
| 作者单位： | 1. 中国药科大学,南京,210009
2. 南京医科大学附属脑科医院,南京,210029 |
| |
| 摘 要： | 胶质瘤(glioma)是中枢神经系统中最常见的一种恶性肿瘤,发病率高,呈浸润性生长,治疗效果差,复发率高,患者平均存活时间为10个月。常规的肿瘤临床治疗方法如手术、化疗、放疗等疗效甚微。随着对基因技术研究的不断加深,如何将基因治疗应用于神经胶质瘤,也成为近年来研究的热点。本文将从自杀基因、免疫基因以及多药耐药基因方面等讨论胶质瘤的基因治疗进展。
|
| 关 键 词： | 神经胶质瘤 基因治疗 自杀基因 免疫基因 多药耐药基因 |
| 文章编号： | 1006-2084（2007）07-0492-03 |
| 收稿时间： | 2006-07-18 |
| 修稿时间： | 2006-07-182007-01-23 |
Research Development of Gene therapy for Glioma |
| |
| ZHAO Liang,XIAO Hong,FENG Fang.Research Development of Gene therapy for Glioma[J].Medical Recapitulate,2007,13(7):492-494. |
| |
| Authors: | ZHAO Liang XIAO Hong FENG Fang |
| |
| Institution: | 1. China Pharmaceutical University, Jiangsu, Nanjing 210009, China ; 2. Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing 210009, China |
| |
| Abstract: | Gliomas are one of the most common malignant tumor in in the central nervous system,which has high incidence,infiltrative growth,poor therapeutic effect and high relapse rate.The mean survival time of patients with this disease is about 10 months.Conventional clinical treatment for this disease such as surgery,chems,radiotherapy and so on has few curative efffect.With the increasing study of gene technique,how to use gene therapy in the treatment of this disease is becoming a hot spot in recent years.This article reviews gene therapeutic progress of glioma in sucide gene,immunogene and multiple resistance gene. |
| |
| Keywords: | Neurospongioma Genetherapy Suicide gene Immunogene Multi-drug resistance gene |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
