| 194例重症手足口病病原学检测及流行病学分析 |
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| 引用本文： | 张中,李梅,刘志峰,陈倩,胡正.194例重症手足口病病原学检测及流行病学分析[J].江苏医药,2012,38(4):450-452. |
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| 作者姓名： | 张中 李梅 刘志峰 陈倩 胡正 |
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| 作者单位： | 张中 (南京医科大学附属南京儿童医院预防保健科,江苏省,210008) ； 李梅 (南京医科大学附属南京儿童医院预防保健科,江苏省,210008) ； 刘志峰 (南京医科大学附属南京儿童医院预防保健科,江苏省,210008) ； 陈倩 (南京医科大学附属南京儿童医院预防保健科,江苏省,210008) ； 胡正 (南京医科大学附属南京儿童医院预防保健科,江苏省,210008) ； |
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| 摘 要： | 目的了解南京地区重症手足口病(HFMD)的流行病学规律,探索正确的应对措施。方法利用国家疾病监测网络直报信息系统,对本地区194例重症HFMD资料进行临床流行病学分析。结果 2009年南京地区重症HFMD的发病率为2.55/10万。其中,外来人口HFMD的发病率为3.13/10万,南京本地为2.20/10万。194例重症HFMD患儿中,3岁以下148例,占76.28%,男女比例为1.85∶1;通过对194例的病原学分析表明,肠道病毒71阳性63例(32.47%),COX A16阳性16例(8.25%)。结论 HFMD患儿,尤其是3岁以下的患儿高发,病程在5d以内发生。应控制感染源,加强HFMD监测,降低重症HFMD病死率。
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| 关 键 词： | 手足口病 肠道病毒71 流行病学 |
Clinical epidemiological characteristics of 194 cases with severe hand-foot-mouth disease in Nanjing China |
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| Institution: | ZHANG Zhong,LI MEI,LIU Zhifeng,et al. Affiliated Nanjing Children′s Hospital,Nanjing Medical University,Nanjing 210008, CHINA |
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| Abstract: | Objective To analyze the epidemiological and clinical characteristics of children with severe hand-foot-mouth disease(HFMD) in Nanjing China. Methods Data of 194 cases with severe HFMD in 2009 were retrospectively analyzed. Results The incidence rate of severe HFMD in Nanjing China was 2.55/100000,which was 3.13/100000 for the migrants and 2.20/100000 for the residents. Of 194 cases,148 cases(76.28%) were aged less than 3 years old,126 cases were male and 68 cases were female with the ratio of male-to-female of 1.85∶1. Sixty-three(32.47%) cases were found to be positive to Enterovirus71 and 16 cases(8.25%) to COX A16. Conclusion Severe HFMD is frequently found in children less than 3 years old and the course of disease is usually within 5 days.It is important to control the infection sources,strengthen the monitoring of HFMD,and reduce the morbility of HFMD. |
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| Keywords: | Hand-foot-mouth disease Enterovirus 71 Epidemiology |
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