IgA肾病患者的肾脏病理学特征 |
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引用本文: | 陈彩妹,王凉,刘斌,祁真,华佳,刘晓斌,尤宇望,张志坚,单炜薇,孙铸兴.IgA肾病患者的肾脏病理学特征[J].江苏医药,2012,38(2):153-155. |
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作者姓名: | 陈彩妹 王凉 刘斌 祁真 华佳 刘晓斌 尤宇望 张志坚 单炜薇 孙铸兴 |
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作者单位: | 陈彩妹 (南京医科大学附属无锡人民医院肾脏病科, 江苏省,214000) ; 王凉 (南京医科大学附属无锡人民医院肾脏病科, 江苏省,214000) ; 刘斌 (南京医科大学附属无锡人民医院肾脏病科, 江苏省,214000) ; 祁真 (南京医科大学附属无锡人民医院肾脏病科, 江苏省,214000) ; 华佳 (南京医科大学附属无锡人民医院肾脏病科, 江苏省,214000) ; 刘晓斌 (南京医科大学附属无锡人民医院肾脏病科, 江苏省,214000) ; 尤宇望 (南京医科大学附属无锡人民医院肾脏病科, 江苏省,214000) ; 张志坚 (南京医科大学附属无锡人民医院肾脏病科, 江苏省,214000) ; 单炜薇 (南京医科大学附属无锡人民医院肾脏病科, 江苏省,214000) ; 孙铸兴 (南京医科大学附属无锡人民医院肾脏病科, 江苏省,214000) ; |
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摘 要: | 目的分析IgA肾病的肾脏病理特点。方法回顾性分析经皮肾穿刺确诊为IgA肾病的407例患者的病理资料。结果 IgA肾病Lee氏分级以Ⅱ级、Ⅲ级为主。病理表现上,局灶节段病变占38.04%,系膜增生型占32.24%,轻微病变型占24.28%。Lee氏分级与免疫荧光沉积强度相关(Z=17.187,P<0.05)。结论 IgA肾病患者的病理表现多样。Lee分级与免疫荧光强度存在一定的相关性。
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关 键 词: | 肾小球肾炎 IgA肾病 |
Pathological characteristics of 407 cases with IgA nephropathy |
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Institution: | CHEN Caimei,WANG Liang,LIU Bin,et al.Department of Nephrology,Affiliated Wuxi People′s Hospital,Nanjing Medical University,Wuxi 214000,CHINA |
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Abstract: | Objective To analyze the pathological characteristics of IgA nephropathy(IgAN).Methods A positive diagnosis of primary IgAN was made after successive native renal biopsies in 407 in-patients.The pathological features of these patients were analyzed retrospectively.ResultsLee′s pathological grades of Ⅱ and Ⅲ were the most common types.Pathologically,focal segmental glomerulonephritis accounted for 38.04%,mesangial proliferative glomerulonephritis for 32.24% and minimal lesion for 24.28% in 407 patients with IgAN.Lee′s classification was correlated to the intensity of IgA deposition(Z=17.187,P<0.05).Conclusion The pathological characteristics of IgAN are varied.There is a correlation between Lee′s classification and the intensity of IgA deposition in IgAN. |
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Keywords: | Glomerulonephritis IgA nephropathy |
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