磁共振弥散加权成像在肝硬化诊断中的应用

目的探讨磁共振弥散加权成像对肝硬化的诊断价值。方法采用GEHDx1．5TMRI扫描仪对100例临床诊断肝硬化患者（肝硬化组）及30名健康对照者（对照组）行轴位屏气弥散加权成像扫描（扩散敏感系数b值选用800mm^2／s），比较2组表观弥散系数（apparent diffusion coefficient。ADC）值。结果对照组与肝硬化组肝脏ADC值分别为（1．842±0．173）和（1．380±0．137）×10^-3mm^2/s,后者低于前者，2组差异有统计学意义。结论肝硬化患者肝脏ADC值下降，磁共振弥散加权成像可望成为无创肝硬化诊断的手段之一。

MR-diffusion-weighted imaging in diagnosis of liver cirrhosis

Objective To investigate the diagnostic value of liver cirrhosis using MR-diffusion-weighted imaging （DWI）. Methods MR-DW1 was performed on 100 cirrhotic patients （cirrhotic group） and 30 healthy controls （control group） using GE HDx 1.5 Tesla MRI scanner when b value was 800 mm^2/s, and the value of apparent diffusion coefficient （ADC） in each group was measured and compared. Results The ADC value of the control group was （1.842±0.173） ×10^-3 mm^2/s, higher than that of the cirrhotic group, which was （1.380±0.137）×10^-3 mm^2/s, and the difference between them was significant. Conclusions The ADC value of cirrhotic patients decreases. MR-DWI may he a promising method for noninvasive diagnosis of liver cirrhosis.