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Severe hyponatremia occurring after surgical stress in a patient with mitochondrial disease
Authors:Nobuko Sasano  Tetsuya Tamura  Takafumi Azami  Hiroshi Sasano
Affiliation:1. Department of Anesthesia, Inabe General Hospital, 771 Ageki, Hokusei-cho, Inabe, Mie, 511-0428, Japan
2. Department of Anesthesia, Kainan Hospital, Aichi, Japan
3. Department of Anesthesiology and Medical Crisis Management, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
Abstract:A 53-year-old man with mitochondrial disease underwent gastrectomy because of gastric cancer. Three days after the surgery, he developed severe hyponatremia (Na, 106 mmol·l?1) together with hypovolemic shock and lactic acidosis. Despite the hyponatremia, his urine sodium concentration was high, suggesting renal salt wasting. Although mitochondrial diseases are not common and hyponatremia in patients with these diseases is not well known, clinicians should pay close attention to serum sodium levels and maintain them properly.
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