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Drawbacks of GENEHUNTER for larger pedigrees: application to panic disorder
Authors:Goedken R  Ludington E  Crowe R  Fyer A J  Hodge S E  Knowles J A  Vieland V J  Weissman M M
Affiliation:Department of Psychiatry, the University of Iowa College of Medicine, Iowa City, Iowa 52242-1000, USA. rhinda-goedken@uiowa.edu
Abstract:Large pedigrees can pose a problem for GENEHUNTER linkage analysis software. Differences in two-point and multipoint lodscores were observed when comparing GENEHUNTER to other linkage software. Careful consideration must be given when selecting linkage analysis programs. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:781-783, 2000.
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