功能性消化不良患者胆囊排空评价

目的:了解功能性消化不良(Functionaldyspepsia,FD)患者胆囊排空功能,探讨胆囊运动与FD的关系。方法:采用放射性核素显像法检测26例功能性消化不良患者(FD组)空腹及试餐后胆囊排空,并与21例正常成人(NC组)空腹及餐后胆囊排空作比较。结果:FD组患者十二指肠显像时间为(43.2±2.6)min,对照组(NC组)为(25.7±3.8)min;空腹及试餐后40,50,60min胆囊排空分数明显低于正常对照组相应时相的胆囊排空分数,有显著性差异。结论:FD患者存在胆囊排空障碍,考虑系胆囊收缩无力和Oddis括约肌运动不协调所致,胆囊排空障碍是功能性消化不良的病理生理基础和病因之一。

GALLBLADDER EMPTYING FUNCTION IN PATIENTS WITH FUNCTIONAL DYSPEPSIA

Objective: To investigate gallbladder emptying function in patients with functional dyspepsia (FD group) and the relation between gallbladder motion and dyspepsia. Methods: The emptying function of precibal and postcibal gallbladder in 26 patients with FD were studied using 99mTc-radionucleography and compared with those of 21 normal controls (NC group). Results: The time for radionucleogram of duodenum in FD group was (43.2±2.6) minutes and NC group (25.7±3.8) minutes after 99mTc-EHIDA-85 MBq administration.The emptying rates of precibal and postcibal gallbladder at 40,50,60 min in FD group were significantly decreased as compared with those of normal controls (P<0.001). Conclusion: Patients with FD seem to have a decreased gallbladder emptying function induced by weak gallbladder contraction and incoordination of Oddis sphincter.This study suggested that abnormal gallbladder emptying is one of basic pathophysiology in FD.