| 多西他赛联合奥沙利铂治疗进展期胃癌的临床观察 |
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| 引用本文： | 粱进,毕清,杨润祥.多西他赛联合奥沙利铂治疗进展期胃癌的临床观察[J].实用癌症杂志,2007,22(5):501-502. |
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| 作者姓名： | 粱进 毕清 杨润祥 |
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| 作者单位： | 云南省肿瘤医院,650118 |
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| 摘 要： | 目的观察多西他赛联合奥沙利铂治疗进展期胃癌的近期疗效和不良反应。方法28例进展期胃癌以多西他赛75mg/m2第1天,奥沙利铂130mg/m2第2天行全身化疗,21～28天为1个周期,2个周期后评价疗效和不良反应。结果28例患者,完全缓解1例,部分缓解14例,稳定9例,进展4例,总有效率为53.57%。结论多西他赛联合奥沙利铂治疗进展期胃癌疗效好,患者生活质量提高,不良反应可耐受,值得在临床上推广。
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| 关 键 词： | 进展期胃癌 化学治疗 多西他赛 奥沙利铂 |
| 文章编号： | 1001-5930（2007）05-0501-02 |
| 修稿时间： | 2007-05-10 |
Clinical Observation in the Treatment of Advanced Gastric Cancer with Docetaxel and Oxaliplatin |
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| LIANG Jin,BI Qing,YANG Run-xiang.Clinical Observation in the Treatment of Advanced Gastric Cancer with Docetaxel and Oxaliplatin[J].The Practical Journal of Cancer,2007,22(5):501-502. |
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| Authors: | LIANG Jin BI Qing YANG Run-xiang |
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| Institution: | Yunnan Tumor Hospital,Kunming,650118 |
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| Abstract: | Objective To study the short-term efficacy and toxicities of docetaxel and oxaliplatin in the treatment of advanced gastric cancer.Methods 28 patients with advanced gastric cancer were treated with docetaxel(75mg/m2,d1),oxaliplatin(130mg/m2,d2).The chemotherapy was repeated every 21 to 28 days.Effacicy and toxicities were evaluated after 2 cycles of chemotherapy.Results There were 1 complete remission(CR),14 partial remission(PR),9 stabilization and 4 progression among 28 patients.The total effective rate was 53.57%.Conclusion Chemotherapy with docetaxel and oxaliplatin is effective in the treatment of patients with advanced gastric cancer with minimal and accepted toxicities. |
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| Keywords: | Advanced gastric carcinosis Chemotherapy Docetaxel Oxaliplatin |
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