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A型肉毒毒素治疗面肌痉挛、眼睑痉挛疗效观察
引用本文:王国栋,赵永波. A型肉毒毒素治疗面肌痉挛、眼睑痉挛疗效观察[J]. 国际神经病学神经外科学杂志, 2009, 36(1): 13-15
作者姓名:王国栋  赵永波
作者单位:上海交通大学附属第一人民医院神经科,上海市,200080;上海交通大学附属第一人民医院神经科,上海市,200080
摘    要:目的观察A型肉毒毒素治疗面肌、眼睑痉挛的疗效。方法采用A型肉毒毒素局部注射治疗偏侧面肌痉挛51例、眼睑痉挛8例,并使用Cohen和Albert量表对疗效进行评估。结果31例(52.5%)症状完全缓解,22例(37.2%)明显改善,6例(10.1%)部分改善,疗效平均持续约9~33周,复发者重复注射仍有效。不良反应可出现眼睑闭合不全、面肌无力、眼睑下垂等共18例,均在4周内恢复。结论局部注射A型肉毒毒素确为一种安全有效的治疗面肌、眼睑痉挛的方法。

关 键 词:A型肉毒毒素  面肌痉挛  眼睑痉挛

Therapeutic effects of botulinum toxin A in patients with hemifacial spasm or blepharospasm
WANG Guo-Dong,ZHAO Yong-Bo. Therapeutic effects of botulinum toxin A in patients with hemifacial spasm or blepharospasm[J]. Journal of International Neurology and Neurosurgery, 2009, 36(1): 13-15
Authors:WANG Guo-Dong  ZHAO Yong-Bo
Abstract:Objective To investigate the therapeutic efficacy of botulinum toxin A in patients with hemifacial spasm patients (HFS) and blepharospasm (BS). Methods A total of 59 patients, including 51 patients with HFS and 8 patients with BS, were enrolled. They received local injections of botulinum toxin A. The therapeutic effects were assessed with Cohen and Albert spasm scale. Results Of the 59 patients with HFS or BS, 31(52.5%) were completely relieved of symptoms, 22(37.2%) were obviously relieved, and 6(10.1.2%)...
Keywords:Botulinum toxin A  Hemifacial spasm  Blepharospasm  
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