| 大鼠视网膜缺血／再灌流损伤导致视网膜节细胞坏死的定量研究 |
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| 引用本文： | 刘忠浩,罗学港,楚亚平,刘求理,帅建中,卢大华,刘丹.大鼠视网膜缺血／再灌流损伤导致视网膜节细胞坏死的定量研究[J].中南大学学报(医学版),1995(6). |
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| 作者姓名： | 刘忠浩 罗学港 楚亚平 刘求理 帅建中 卢大华 刘丹 |
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| 作者单位： | Liu Zhonghao; Luo Xuegang ;Chu Yaping
(Laboratory of Neurobiology，Hunan Medical University |
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| 摘 要： | 用大鼠人工眼高压模型，比较观察眼高压所致缺血视网膜（ＩＲ）与缺血／再灌流视网膜（ＩＲＲ）中坏死视网膜节细胞的数量（密度）差异及坏死节细胞在ＩＲＲ中的分布规律。结果表明：ＩＲＲ中的坏死节细胞远比ＩＲ中的为多（Ｐ＜０．０１）；ＩＲＲ４象限中坏死节细胞密度差异无显著性。
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| 关 键 词： | 高眼压 局部缺血 再灌注损伤 视网膜神经节细胞 锥虫蓝 大鼠 |
A QUANTITATIVE STUDY ON THE RETINAL GANGLION CELL NECROSIS INDUCED BY
ISCHEMIA/REPERFUSION DAMAGE IN RATS |
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| Liu Zhonghao, Luo Xuegang ,Chu Yaping.A QUANTITATIVE STUDY ON THE RETINAL GANGLION CELL NECROSIS INDUCED BY
ISCHEMIA/REPERFUSION DAMAGE IN RATS[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),1995(6). |
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| Authors: | Liu Zhonghao Luo Xuegang Chu Yaping |
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| Abstract: | In attempt to
demonstrate the serious effects of postischemic damage,a comparativestudy focused on
retinal ganglion cell(RGC)between the left simple ischemia retinas(IR)andright
ischemia/reperfusion retinas(IRR)was made in the same rat(Wistar).(n=21)Theresults showed
that the cell death of RGC in the IRR group was far more severe than that inthe IR group
(P<0.01),but no retinal quadrant characters involved in the distribution ofnecrotic RGC was
observed in the IRR. |
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| Keywords: | ocular hypertension ischemia reperfusion injury \reinal ganglioncells trypan blue rats |
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