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Chronic kidney disease in pregnancy
Affiliation:1. Division of Obstetrical Anesthesia, Sunnybrook Health Sciences Centre, Toronto, Canada;2. University of Toronto Obstetrical Anesthesia Research Unit, Sunnybrook Health Sciences Centre, Toronto, Canada;1. Centre for Infectious Diseases and Control (MKR, ARG), Bioinformatics Division (SSL), School of Bio Sciences and Technology, VIT University, Vellore, Tamil Nadu, India;1. Department of Medicine, Division of Nephrology, Brazil;2. Obstetrics, Federal University of Sao Paulo (UNIFESP), Brazil;1. Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, TN;2. Division of Nephrology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Abstract:Parturients with renal insufficiency or failure present a significant challenge for the anesthesiologist. Impaired renal function compromises fertility and increases both maternal and fetal morbidity and mortality. Close communication amongst medical specialists, including nephrologists, obstetricians, neonatologists and anesthesiologists is required to ensure the safety of mother and child. Pre-existing diseases should be optimized and close surveillance of maternal and fetal condition is required. Kidney function may deteriorate during pregnancy, necessitating early intervention. The goal is to maintain hemodynamic and physiologic stability while the demands of the pregnancy change. Drugs that may adversely affect the fetus, are nephrotoxic or are dependent on renal elimination should be avoided.
Keywords:Obstetrical anesthesia  Renal failure  Epidural anesthesia  Pregnancy
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