The effects of background noise on brain activity using speech stimuli on healthy young adults |
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| Institution: | 1. Diagnostic Imaging and Radiotherapy Program, School of Diagnostic and Applied Health Sciences, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia;3. Audiology Program, School of Rehabilitation Sciences, Faculty of Health Sciences, National University of Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia;1. Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing 100191, China;2. National Institute on Drug Dependence and Beijing Key Laboratory of Drug Dependence, Peking University, Beijing 100191, China;3. Peking-Tsinghua Center for Life Sciences and PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing 100871, China;1. School of Medicine, Washington University in St. Louis, St. Louis, Missouri;2. Department of Psychology, San Diego State University, San Diego, California;3. Department of Psychiatry, University of California San Diego, San Diego, California;4. Development & Emotion Branch, National Institute of Mental Health, Bethesda, Maryland;1. Departments of Psychiatry, Recep Tayyip Erdogan University, School of Medicine, Rize, Turkey;2. Departments of Psychiatry, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey;3. Departments of Microbiology, Recep Tayyip Erdogan University, School of Medicine, Rize, Turkey;4. Departments of Psychiatry, Afyonkarahisar State Hopital, Afyonkarahisar, Turkey;1. Department of Neuroscience, Karolinska Institute, Stockholm, Sweden;2. Russian Academy of Sciences, St. Petersburg Institute for Informatics and Automation, Saint Petersburg, Russia;3. School of Anatomical Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa;4. Department of Cell Biology, Faculty of Sciences, University of Málaga, Spain;5. Laboratory of Eukaryotic Gene Expression and Signal Transduction (LEGEST), Ghent University-Gent, Belgium;6. Department of Physiology, School of Medicine, University of Málaga, Spain;7. Laboratory of Drug Addiction Pharmacology, Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Smetna 12, PL 31-343 Kraków, Poland;8. Department of Clinical and Experimental Medicine, Pharmacology Section, University of Ferrara, Italy;9. Department of Human Anatomy and Physiology, University of Padova, Italy;10. Department of Biophysic, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, México, DF, Mexico;11. IRCCS Lido Venice, Italy;12. Department of Toxicology, Faculty of Pharmacy, Jagiellonian University, Kraków, Poland;1. National Centre for Register-Based Research, University of Aarhus, Denmark;2. Mental Health Centre Copenhagen, Copenhagen University, Faculty of Health Sciences, Denmark |
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| Abstract: | Everyday spoken language processing does not occur in a novel acoustic environment, but rather in the presence of the interfering background noise. In the present study, brain activation associated with speech perception (SP) processing in quiet (SPQ) and SP processing in 5-dB SNR noise (SPN) was examined in 15 healthy young adults using functional MRI. The behavioral performance shows no significant difference between SPN and SPQ, suggesting that background noise does not always impair spoken language comprehension in young healthy participants. The fMRI results indicate that both the superior temporal gyrus (STG) and middle temporal gyrus (MTG) were significantly activated during both the SPQ and SPN. This is attributed to the use of verbal stimuli in this study. Further activation for both SPQ and SPN was also found in other temporal areas and the cerebellum. However interestingly, specific comparisons between SPQ and SPN revealed significant increases in brain activation in the left STG, left MTG and bilateral cerebellum during SPN compared to SPQ. We suggest that the higher processing demands due to the presence of background noise are associated with compensatory strategies to allow the cognitive system to overcome noise-related interference, particularly implicating involvement of the left STG, left MTG and bilateral cerebellum. Findings are discussed in the context of corroborating evidence of such compensation. |
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| Keywords: | fMRI Speech perception STG MTG Compensatory strategy |
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