A rare case of inguinolabial lipoblastoma in a 13-month-old female |
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| Institution: | 1. Section of Pediatric and Adolescent Gynecology, Gynecology Clinic, The Hospital for Sick Children and University of Toronto, 7th floor Black Wing, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8;2. Walter Reed National Military Medical Center, Bethesda, Maryland;3. Division of Urology, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada;1. Department of Gynecology-Obstetrics and Reproductive Medicine, Intercommunal Hospital-University Paris XII Créteil, Créteil, France;2. Department of Maxillofacial and Plastic and Reconstructive Surgery, Henri Mondor Hospital, Créteil, France;3. Department of Radiology, Lariboisière Hospital, Assistance publique des hôpitaux de paris, Paris, France;1. Department of Pediatric Surgery, Mashhad University of Medical Science, Mashhad, Iran;2. Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran;3. Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Science, Mashhad, Iran;1. Department of Obstetrics and Gynecology, Dokkyo Medical University Saitama Medical Center, Koshigaya, Japan;2. Department of Pathology, Dokkyo Medical University, Saitama Medical Center, Koshigaya, Japan;3. Department of Pediatric Surgery, Dokkyo Medical University, Saitama Medical Center, Koshigaya, Japan;1. Department of Gynecology and Gynecologic Oncology, Medical University of Białystok, Białystok, Poland;2. Medical University Teaching Hospital, Białystok, Poland;3. Department of Gynecology and Obstetrics, Faculty of Medicine, University of Warmia and Mazury, Olsztyn, Poland |
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| Abstract: | Lipoblastoma is a rare, rapidly growing, benign mesenchymal tumor composed of various stages of maturing adipocytes that most often occurs in children under the age of 3. The common locations are the extremities and the trunk. Presentation in the genitoinguinal area is rare. We report a case of a 13-month-old female infant with a 4-month history of a progressively enlarging left labial mass that encompassed her left labium majora and inguinal region. Pelvic MRI confirmed growth from previous ultrasound size of 3 × 2 × 1 cm to 7 × 2 × 2 cm. Composition was suggestive of adipose tissue. The mass was excised through a left inguinal incision. The final pathology results described a lipoblastoma. Six year follow-up has not revealed any signs or symptoms of recurrence.Circumscribed lipoblastomas should be distinguished from their infiltrative counterpart, diffuse lipoblastoma or lipoblastomatosis, which can be more difficult to excise and thus, more likely to recur. Lipoblastoma should also be distinguished from myxoid liposarcoma, which has malignant features, carries a high risk of recurrence, and requires a more aggressive management protocol. Although rare, lipoblastoma should be considered as part of the differential diagnosis of a rapidly growing vulvar mass in prepubertal children. |
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