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Disseminated Enteroviral Infection Associated with Obinutuzumab |
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| Authors: | Claire Dendle Michael Gilbertson Tony M. Korman Vera Golder Eric Morand Stephen Opat |
| Affiliation: | Monash Health, Clayton, Victoria, Australia (C. Dendle, M. Gilbertson, T.M. Korman, V. Golder, E. Morand, S. Opat); ;Monash University, Clayton (C. Dendle, T.M. Korman, V. Golder, E. Morand, S. Opat) |
| Abstract: | Two cases of disseminated enteroviral infection occurred in patients who received the CD20 monoclonal antibody obinutuzumab. Clinical features included hepatitis, edema, and a dermatomyositis-like syndrome. These manifestations may be unfamiliar to clinicians and are possibly responsive to intravenous immunoglobulin. Clinicians should remain vigilant for enteroviral infections in patients receiving obinutuzumab. |
| Keywords: | obinutuzumab CD 20 monoclonal antibody enterovirus dermatomyositis rituximab viruses |