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人体乳腺硬癌癌细胞器形态结构的定量研究
引用本文:王勇,陈平,文小玲,杨承纲,韩丹,刘爱武,张季,刘美玉,李维波. 人体乳腺硬癌癌细胞器形态结构的定量研究[J]. 中国医学物理学杂志, 2007, 24(6): 428-429
作者姓名:王勇  陈平  文小玲  杨承纲  韩丹  刘爱武  张季  刘美玉  李维波
作者单位:1. 昆明医学院,物理数学教研室,云南,昆明,650031
2. 昆明医学院,第三附属医院,云南,昆明,650031
3. 昆明医学院,电子显微镜室,云南,昆明,650031
基金项目:云南省教育厅基础研究基金
摘    要:目的:区分乳腺正常细胞器和各期乳腺癌细胞器之间的差异,从而建立检查量化指标。方法:本文对女性乳腺硬癌癌细胞器线粒体,溶酶体的16个形态参数进行体视学统计分析。结果:发现癌细胞与正常细胞比较,其线粒体、溶酶体的体积、表面积和面数密度等形态参数存在高度显著差异和显著差异。结论:探讨了癌细胞的线粒体,溶酶体形态变异与功能之间的关系,为乳腺癌临床诊断提供了重要的定量依据。

关 键 词:体视学  线粒体  溶酶体
文章编号:1005-202X(2007)06-0428-02
收稿时间:2007-04-13
修稿时间:2007-04-13

A Fixed Amount Research About the Hard Cancer Cell in Breast Carcinoma
WANG Yong,CHEN Ping,WEN Xiao-ling,YANG Cheng-gang,HAN Dan,LIU Ai-wu,ZHANG Ji,LIU Mei-yu,LI Wei-bo. A Fixed Amount Research About the Hard Cancer Cell in Breast Carcinoma[J]. Chinese Journal of Medical Physics, 2007, 24(6): 428-429
Authors:WANG Yong  CHEN Ping  WEN Xiao-ling  YANG Cheng-gang  HAN Dan  LIU Ai-wu  ZHANG Ji  LIU Mei-yu  LI Wei-bo
Affiliation:1 .Department of Physics and Mathematics, Kunming Medical College, Kunming Yunnan 650031, China; 2.Electron Microscopy Lab, Kunming Medical College, Kunming Yunnan 650031, China; 3.The Third Affiliated Hospital of Kunming Medical College, Kunming Yunnan 650031, China
Abstract:Objective: For dislinguishing analyse normal cells and cancerous cells of the breast difference and establishment check index. Methods: Stereological method was applied in statistics and analyzing 16 ultrastructure morphological parameters of the mitochondrion and lysosome in 3 cases of the breast carcinoma. Results: Compared with normal cells, significant differences were found with 16 morphological parameters such as volume density, numerical density on area and specific surface density. Conclusions: It provides a quantitative basis of auxiliary distinguish for the clinical diagnosis of the breast carcinoma.
Keywords:stereology  mitochondrion  lysosome
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