303例颌下腺肿瘤临床病理分析

目的：了解颌下腺肿瘤的组织学类型、构成比及发病性别、年龄、体积、复发等临床病理特征。方法：对303例颌下腺肿瘤临床病理资料进行统计分析。结果：良性上皮性肿瘤216例（71.29%）,恶性上皮性肿瘤79例（26.07%）,软组织肿瘤6例（1.98%）,淋巴造血系统肿瘤2例（0.66%）。多形性腺瘤、肌上皮瘤和Warthin瘤居良性上皮性肿瘤的前3位,腺样囊性癌、癌在多形性腺瘤中、黏液表皮样癌和腺泡细胞癌居恶性上皮性肿瘤的前4位。良、恶性上皮性肿瘤的男女比为0.79∶1和1.82∶1;平均年龄为37.5岁和47.8岁;平均直径为2.55 cm和3.43cm。颌下腺肿瘤复发率为6.93%,复发性多形性腺瘤占76.19%。结论：多形性腺瘤和腺样囊性癌分别是最常见的良、恶性上皮性肿瘤;良性上皮性肿瘤多见于女性,恶性上皮性肿瘤多见于男性;恶性上皮性肿瘤的发病年龄和体积均大于良性;多形性腺瘤易复发。

Clinicopathological Analysis of 303 Cases of Submandibular Gland Tumors.

Objective： To investigate clinicopathological characteristics such as the type of histology, the eonstituent ratio, the distribution of sex, age, size and recurrence of submandibular gland tumors （SGT）. Methods： The clinical and pathological data of 303 eases of SGT were statistically analysed. Results： 216 cases （71.29% ） were benigh epithelial tumors; 79 cases （26.07%） were malignant epithelial tumors; 6 cases （1. 98%） were soft tissue tumors; 2 cases （0. 66%） were haematolymphoid tumors. Pleomorphic adenoma, myoepithelioma and Warthin tumor were the mostly encountered three types of benign epithelial tumors. Adenoid cystic carcinoma, carcinoma ex pleomorphic adenoma, mucoepidermoid carcinoma and acinic cell carcinoma were the mostly encountered four types of malignant epithelial tumors. The ratio of male to female of benign and malignant epithelial tumors was 0.79 ; 1 and 1.82 ; 1 respectively. The average age of benign epithelial tumors was 37.5 years old, while the average age of malignant tumors was 47.8 years old. The average diameter of benign and malignant epithelial tumors was 2.55cm and 3.43cm, respectively. The recurrence rate of SGT was 6.93%, among which the recurrent pleomorphic adenoma accounted 76.2%. Conclusion： Pleomorphic adenoma and adenoid cystic ca racinoma are the most common type of benign and malignant epithelial SGT, respectively. Benign epithelial tumors are more common in women, while ma lignant epithelial tumors are more common in men. The onset age of malignant epithelial tumors is later than benign epithelial tumors. The size of malignant epithelial tumors is larger than benign epithelial tumors. Recurrences appear to be much more likely in pleomorphic adenoma.