鼻内镜下聚焦超声与射频消融治疗变应性鼻炎疗效比较分析

目的:观察鼻内镜下分别使用高能聚焦超声治疗仪及低温射频消融仪治疗变应性鼻炎的疗效。方法:将179例变应性鼻炎患者分为聚焦超声组84例和射频消融组95例,记录患者治疗前后症状和体征变化并加以评分,随访观察比较2组治疗效果。结果:聚焦超声组术前症状及体征评分为(10.84±2.26)分,术后12个月评分为(4.65±1.76)分,其评分较术前明显降低(P<0.01)。射频消融组术前症状及体征评分为(10.02±2.05)分,术后12个月评分为(5.32±1.37)分,其评分较术前显著降低(P<0.01)。2组患者术后随访1年,总有效率分别为86.9%和73.7%,差异有统计学意义(P<0.05)。结论:高能聚焦超声与低温射频消融均是治疗变应性鼻炎的有效物理方法,1年内治疗效果确切。但高能聚焦超声创伤小,可反复治疗,且1年后治疗效果更持久。

Effect comparison of the focused ultrasound and radiofrequency ablation under nasal endoscope in the treatment of allergic rhinitis

Objective:To observe the effects of high intensity focused ultrasound and low temperature radiofrequency ablation under nasal endoscope in the treatment of allergic rhinitis. Methods:One hundred and seventy-nine patients with allergic rhinitis were divided into the focused ultrasound group(FU group,84 cases) and radiofrequency ablation group(RFA group,95 cases). The symptoms and signs in all patients were recorded and scored before and after treatment,and the therapeutic effects between two groups were analyzed. Results:The score of the symptoms and signs in FU group before treatment(10. 84 ± 2. 26) was significantly higher than that after 12 monthsoftreatment(4.65±1.76)(P<0.01).ThescoreofthesymptomsandsignsinRFAgroupbeforetreatment(10.02±2.05) was significantly higher than that after 12 months of treatment(5. 32 ± 1. 37)(P<0. 01). Two groups were followed up for 1 year. The total effective rates in FU and RFA group were 86. 9% and 73. 7%,respectively,the difference of which was statistically significant(P<0. 05). Conclusions:The high intensity focused ultrasound and radiofrequency ablation are the effective physical methods in treating allergic rhinitis,especially within 1 year. The treatment of allergic rhinitis with focused ultrasound is less trauma,can be repeated,and its curative effect is more durable after 1 year.