同型半胱氨酸、超敏C反应蛋白、低密度脂蛋白、三酰甘油、总胆固醇与急性脑梗死的关系研究

目的:研究同型半胱氨酸(Hcy)、超敏C反应蛋白(hs-CRP)、低密度脂蛋白(LDL-C)、三酰甘油(TG)及总胆固醇(TC)的水平与急性脑梗死(ACI)发病的关系。方法:搜集61例ACI患者(ACI组)和32例同期住院治疗的非脑血管病患者(对照组)的血液标本,比较2组Hcy、hs-CRP、LDL-C、TG及TC水平,并分析Hcy与hs-CRP、LDL-C、TG、TC的相关性。结果:ACI组血清Hcy、hs-CRP、LDL-C、TG及TC水平较对照组均升高 (P<0.05~P<0.01);Hcy与hs-CRP、LDL-C、TG、TC均无明显相关关系(P >0.05)。结论:ACI患者的血清Hcy、hs-CRP、LDL-C、TG 与TC水平均较对照组升高,均是脑梗死发病的重要危险因素。

The relationships between the levels of homocysteine,hypersensitive C reactive protein,low-density lipoprotein cholesterol,triglycerides and total cholesterol and acute cerebral infarction

Objective:To investigate the relationships between the levels of homocysteine( Hcy) ,hypersensitive C reactive protein( hs-CRP),low density lipoprotein(LDL-C),triglyceride(TG) and total cholesterol(TC) and acute cerebral infarction(ACI). Methods:Sixty-one patients with ACI and 32 patients without cerebrovascular disease were divided into the ACI group and control group. The levels of Hcy,hs-CRP,LDL-C,TG and TC in two groups were compared. The correlation of the levels of Hcy,hs-CRP,LDL-C,TG and TC with the occurrence of acute cerebral infarction were analyzed. Results:Compared with the control group,the levels of serum Hcy, hs-CRP,LDL-C,TG and TC in ACI group increased(P<0. 05 to and P<0. 01). The obvious correlation of Hcy with hs-CRP,TG, LDL-C and TC did not found(P>0. 05). Conclusions:The levels of the serum Hcy,hs-CRP,LDL-C,TG and TC in patients with acute cerebral infarction increased significantly,whose were the important risk factors of the occurence of cerebral infarction.