| 烧伤瘢痕的形成机制与防治 |
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| 引用本文： | 徐阳成,罗成群. 烧伤瘢痕的形成机制与防治[J]. 中国烧伤创疡杂志, 2003, 15(4): 354-357 |
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| 作者姓名： | 徐阳成 罗成群 |
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| 作者单位： | 中南大学湘雅三医院烧伤整形科,湖南,长沙,410013 |
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| 摘 要： | 在传统的烧伤治疗中，深度烧伤不可避免形成病理性瘢痕，由于病理性瘢痕形成机制尚未完全明确，成为目前困扰临床治疗日益突出的问题。本文从生长因子、细胞凋亡及基因芯片技术三方面对瘢痕形成机制的探讨，论述了瘢痕可能的形成机制以及相应的防治措施，提出随着瘢痕形成机制的进一步明确及烧伤医疗技术的进步，有望从根本上预防瘢痕的发生。
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| 关 键 词： | 瘢痕 生长因子 细胞凋亡 基因芯片 |
| 文章编号： | 1001-0726(2003)03-0354-04 |
| 修稿时间： | 2003-01-14 |
The mechanism of the formation of burn scar and its prevention and treatment |
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| XU Yang-cheng,revised by LUO Cheng-qun,Dept. of Burns and Plastic Surgery,The rd Xiangya Hospital,Central South University,Changsha,HunanProvince ,China. The mechanism of the formation of burn scar and its prevention and treatment[J]. The Chinese Journal of Burns Wounds & Surface Ulcers, 2003, 15(4): 354-357 |
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| Authors: | XU Yang-cheng revised by LUO Cheng-qun Dept. of Burns Plastic Surgery The rd Xiangya Hospital Central South University Changsha HunanProvince China |
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| Affiliation: | XU Yang-cheng,revised by LUO Cheng-qun,Dept. of Burns and Plastic Surgery,The 3rd Xiangya Hospital,Central South University,Changsha,HunanProvince 410013,China |
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| Abstract: | Objective:When deep burn wound is treated with conventional treatment, it is inevitable that pathogenic scars will form. The mechanism of scar formation is not yet very clear. Scar is a big problem, which makes clinicians puzzled. This paper is trying to explain the mechanism of scar formation in three aspects, i.e. growing factors, cell apoptosis and gene chip technology, to discuss the possible mechanism of scar formation and to propose relevant measures for its prevention and treatment. As the mechanism of scar formation isbecoming more and more clear, and burn medicine is making progress, it is hopefully that the formation of scar an be radically prevented. |
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| Keywords: | Scar growing factor cell apoptosis gene chip |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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