1668例住院患者抗生素使用分析

目的对1668例住院患者抗生素使用情况进行分析,为制定合理使用抗生素规范提供依据.方法采用整群随机抽样法对我院2003年1-12月1668例住院患者抗生素使用情况进行分析.结果 1668例中使用抗生素者1247例,使用率为74.76%,送细菌药物敏感试验76例,占使用抗生素人数的6.09%,使用抗生素过程中发生医院感染39例,占3.12%.不合理使用抗生素共297例,占23.81%;其中无指征或指征不强131例(38.04%);抗生素联用过多93例(31.31%);抗生素使用时间过长27例(9.09%);抗生素使用过程中更换频繁24例(8.08%);同类抗生素联用不合理22例(7.40%).结论住院患者中有抗生素使用不当情况,应提高临床医务工作人员对正确使用抗生素的认识.

Survey of antibiotic administration in 1 668 patients

Objective To study the current status of antibiotic usage in Southwest hospital, so as to improve the rationality in applying antibiotic. Methods A total of 1 668 patients in Southwest hospital during Jan 1 to Dec 30, 2003 were investigated in antibiotic usage and the data were sorted and analyzed. Results Antibiotics were administered in 1 247 cases (74.76%), including only 76 cases (6.09%) based on susceptibility test, 39 cases (3.12%) occurred hospital infection. 297 cases (23.81%) abused antibiotics, among which 131 cases (38.04%) were without definite symptoms or with weak signs, 93 cases (31.31%) used more than two kinds of antibiotics, 24 cases (8.08%) frequently changed antibiotic in the treatment, 27 cases (9.09%) inappropriately prolonged administration and 22 cases (7.40%) improperly combined the same antibiotics. Conclusion Irrational utilization of antibiotics exits in clinical work. Therefore, the rational use of antibiotic based on susceptibility tests should be emphasized.