| 达那唑治疗慢性阻塞性肺疾病稳定期的疗效 |
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| 引用本文： | 李永锋,张彩凤,许志强,韩鹏,连晓峰,贾明勇.达那唑治疗慢性阻塞性肺疾病稳定期的疗效[J].中国医药指南,2012,10(19):43-44. |
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| 作者姓名： | 李永锋 张彩凤 许志强 韩鹏 连晓峰 贾明勇 |
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| 作者单位： | 1. 河南省濮阳市安阳地区医院呼吸与危重症医学科,河南,安阳,455000
2. 新乡医学院第一附属医院消化内科,河南,卫辉,453100 |
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| 摘 要： | 目的观察达那唑治疗慢性阻塞性肺病(COPD)稳定期的疗效。方法选择COPD稳定期患者68例,随机分为对照组和治疗组各34例。对照组予常规治疗,治疗组予达那唑8~10mg/(kg d)(≤0.4/d),分3次口服;治疗3个月并随访1年。比较肺功能、生活质量评分、1年内再入院情况。结果治疗组比对照组改善明显,差异有统计学意义(P<0.05)。结论达那唑治疗COPD稳定期患者能延缓肺功能下降速度,提高生活质量,降低1年内再入院风险。
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| 关 键 词： | 达那唑 慢性阻塞性肺疾病 |
Effect of Danazol on Stable Stage of Chronic Obstructive Pulmonary Disease |
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| LI Yong-feng
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ZHANG Cai-feng
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XU Zhi-qiang
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HAN Peng
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LIAN Xiao-feng
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JIA Ming-yong.Effect of Danazol on Stable Stage of Chronic Obstructive Pulmonary Disease[J].Guide of China Medicine,2012,10(19):43-44. |
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| Authors: | LI Yong-feng ZHANG Cai-feng XU Zhi-qiang HAN Peng LIAN Xiao-feng JIA Ming-yong |
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| Institution: | 1 Respiratory and Critical Care Medicine Division, Anyang District Hospitals of Puyang, Anyang 455000, China; 2 Department of Gastroenterology, First Affiliated Hospital of Xinxiang Medical, Weihui 45.3100, China) |
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| Abstract: | Objeetive Observe effect of danazol on stable stage of chronic obstructive pulmonary disease （COPD） . Methods 68 patients with stable stage of COPD were randomly divided into control and treatment group. 34 patients in control group were given foundational treatment, the other were given danazol 8-10mg/ （kg.d） （≤0.4/d） po 3 months and followed up one year. Pulmonary function and life quality, a：ad admission to hospital in one year were compared. Results Pulmonary function in 3 months and one year, life quality and admission to hospital in treatment group were improved significantly, which has statistically significant （P〈0.05） compared with control group. Conclusion Danazol slow decline rate c,f lung function, improve life quality and reduce admission to hospital in one year of stable stage of COPD. |
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| Keywords: | Danazol Chronic obstructive pulmonary disease |
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