| 检测血清与腹水血管内皮生长因子对消化系恶性肿瘤的诊断价值 |
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| 引用本文： | 郑黎,陈卫昌,严苏,彭群新. 检测血清与腹水血管内皮生长因子对消化系恶性肿瘤的诊断价值[J]. 临床内科杂志, 2004, 21(7): 463-464 |
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| 作者姓名： | 郑黎 陈卫昌 严苏 彭群新 |
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| 作者单位： | 215006,苏州大学附属第一医院消化内科;215006,苏州大学附属第一医院消化内科;215006,苏州大学附属第一医院消化内科;215006,苏州大学附属第一医院消化内科 |
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| 基金项目： | 江苏省 1 35重点人才课题资助 (基金编号 :37RC2 0 0 2 0 37) |
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| 摘 要： | 目的 探讨检测血清与腹水血管内皮生长因子 (VEGF)对消化系恶性肿瘤的诊断及良、恶性腹水鉴别诊断的价值。方法 采用酶联免疫吸附法 (ELISA法 )检测 5 8例消化系疾病患者血清与腹水VEGF含量。结果 消化系肿瘤患者血清与腹水中VEGF含量明显高于良性疾病患者 (P <0 .0 1)。联合检测血清与腹水VEGF含量 ,其诊断肿瘤性腹水的敏感性较单独检测腹水VEGF有明显提高 (P <0 .0 5 )。结论 血清与腹水VEGF检测有助于消化系恶性肿瘤的临床诊断和良恶性腹水的鉴别诊断
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| 关 键 词： | 血管内皮生长因子 腹水 肿瘤/诊断 |
| 文章编号： | 1001-9057(2004)07-0463-02 |
| 修稿时间： | 2004-01-29 |
The diagnostic value of the vascular endothelial growth factor in serum and ascites |
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| ZHENG Li,CHEN Weichang,YANG Su,et al.. The diagnostic value of the vascular endothelial growth factor in serum and ascites[J]. Journal of Clinical Internal Medicine, 2004, 21(7): 463-464 |
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| Authors: | ZHENG Li CHEN Weichang YANG Su et al. |
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| Affiliation: | ZHENG Li,CHEN Weichang,YANG Su,et al.Department of Gastroenterology,The First Affiliated Hospital of Soochow University,Suzhou 215006,China |
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| Abstract: | Objective To approach the diagnostic and differential diagnostic values of serum and ascites VEGF measurement for the alimentary tract malignant tumors with the ascites.Methods The VEGF levels in serum and ascites were measured by ELISA in 58 specimens.Results The serum and ascites VEGF levels in the alimentary tract malignant tumors were significantly higher than those in benign diseases( P <0.01) The sensitivity to diagnose the malignant ascites by combining serum and ascites VEGF was obviously increased compared to ascites VEGF level alone( P <0.05).Conclusion The serum and ascites VEGF levels may contribute to diagnosis of the alimentary tract malignant tumors and the differential diagnosis of the ascites. |
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| Keywords: | Vascular endothelial growth factor Ascites Neoplasms/diagnosis |
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