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Remote intrapulmonary spread of recurrent respiratory papillomatosis with malignant transformation |
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| Authors: | Katz Sherri L Das Prabodh Ngan Bo-Yee Manson David Pappo Alberto S Sweezey Neil B Solomon Melinda P |
| Affiliation: | Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada. |
| Abstract: | Recurrent respiratory papillomatosis is the most common neoplasm of the larynx in childhood. Extension into lung parenchyma occurs in less than 1% of patients and has a low risk of malignant transformation. Treatment options for intrapulmonary spread have shown limited success. We describe a case of recurrent respiratory papillomatosis with extensive parenchymal involvement and adenosquamous carcinoma in a 14-year-old girl. |
| Keywords: | recurrent respiratory papillomatosis pulmonary parenchymal involvement pulmonary nodules human papilloma virus cidofovir malignant transformation adenosquamous carcinoma |
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