血糖、白细胞和C-反应蛋白水平在急性有机磷中毒患者静脉血中的变化

目的：探讨急性有机磷农药中毒患血糖，白细胞，中性粒细胞和C－反应蛋白水平的变化及临床意义。方法：患入抢救室后，根据中毒的程度分为轻度，中度，重度3组，健康体检作为对照组，分别抽静脉血检测血糖，白细胞，中性粒细胞和C－反应蛋白。结果：中度和重度中毒组血糖，白细胞，中性粒细胞和C－反应蛋白水平均显高于对照组（P＜0．01，P＜0．05），轻度中毒组各项指标无显差异。重度中毒组随病情加重，各项指标呈上升趋势，中度中毒组则随病情减轻，各项指标呈下降趋势。结论：急性有机磷农药中毒患血糖，白细胞，中性粒细胞和C－反应蛋白水平的升高与中毒的程度呈正相关，血糖，白细胞，中性粒细胞和C－反应蛋白的水平越高，并发症及病死率也越高。这对指导治疗，减少并发症的降低病死率有一定意义。

Changes of blood sugar, leukocytes and C-reactive protein in venous blood of patients with acute organophorus poisoning

Objective:To investigate the changes of blood sugar (BS), white blood cells (WBC), granulocytes (GRAN) and C-reactive protein (CRP) in patients with acute organophorus poisoning (AOPP). Methods: Patients were divided into 3 groups: light, moderate and severe degrees of poisoning in emergency room. Healthy volunteers were taken as control. Venous blood was obtained to detect the BS, WBC, GRAN and CRP. Results:The levels of BS, WBC, GRAN and CRP were significantly higher in moderate degree and severe degree groups than that in control group (P<0. 01,P<0. 05), but had no difference in light group. All of them increased with further development of the AOPP in the severe degree group, but decreased with the release of the AOPP in the moderate degree group. Conclusion:The levels of BS, WBS, GRAN and CRP coincide with the degree of poisoning. The higher the levels of BS, WBS, GRAN and CRP, the higher the complication and mortality rate are. These facts are helpful for instructing treatment and reducing the complication and mortality rate.