甲型肝炎病毒感染的血清流行病学研究

对543例城、乡正常人群甲肝IgG抗体的IAHA检测指出阳性率为64.8%。男女差异无显著性（P>0.05）。约半数感染人群发生在10岁以前，到成年时已超过80%。农村较城市更高（P<0.001），多数感染（73.2%）发生在10岁以下的小年龄人群，城市感染则多发生在较大年龄人群，与农村不同。表明甲肝感染普遍而严重。包括幼儿在内的青少年应是防止甲肝感染的主要对象，控制这些易感人群集中单位的爆发流行，是降低甲肝发病的有力措施。成人的群体免疫力较强，主要是及时发现，处理好散在发生的甲肝患者及其密切接触的易感人群，防止造成流行是有积极意义的。

A Seroepidemiological Study of Hepatitis A Viral Infection

Sera of 543 healthy persons from urban and rural areas in Guiyang, Guizhou province were tested for antibody against hepatitis A antigen (anti-HAV IgG) by means of immune adherence hemagglutination. Among them 64.8% were anti-HAV positive. There was no significant difference in antibody level between males and females (p>0.05). Although the anti-HAV positive rates in the rural population were much higher than that in the urban population (p<0.001), the infection rates increased as age went up. Half of the persons under-10 years were infected. Among adults, the anti-HAV positive rates were more than 80%. However, there were differences in the two areas. Hepatitis A mainly infcted older children in urban areas while it mainly involved the younger ones (including the youngest) in rural areas.