Two cases of radiation-induced sarcoma after radiation therapy in nasopharyngeal carcinoma |
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| Authors: | Okoshi Akira Shiga Kiyoto Sasaki Kazuha Asada Yukinori Nishikawa Hitoshi Kobayashi Toshimitsu Watanabe Mika |
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| Affiliation: | Department of Otolaryngology-Head & Neck Surgery, Tohoku University Hospital, Sendai. |
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| Abstract: | We report two cases of radiation-induced sarcoma after chemoradiation therapy in nasopharyngeal carcinoma. Case 1: A 40-year-old man developed a malignant peripheral nerve sheath tumor (MPNST) in the posterior floor of the nasal cavity 10 years after treatment for nasopharyngeal cancer. Case 2: A 64 year-old man developed a malignant fibrous histiocytoma (MFH) of the lower gum 10 years after treatment of nasopharyngeal cancer. Despite radical surgery, the man with MPNST had a recurrent tumor and died of the disease. |
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