右美托咪定辅助镇静对全身麻醉患者术后睡眠功能的影响分析

目的:探讨右美托咪定辅助镇静对全身麻醉患者术后睡眠功能的影响。方法:选取2017年12月至2018年12月期间重庆市长寿区人民医院收治的全身麻醉胃肠手术患者78例作为研究对象,按照随机数字表法分为对照组和观察组,每组39例。对照组给予丙泊酚全麻,观察组在对照组的基础上给予右美托咪定辅助全麻。观察比较2组患者术后1 d、4 d、7 d的AIS失眠评分、拔管后10 min、20 min的Ramsay镇静评分及不良反应发生率。结果:术后1 d,2组患者的AIS失眠评分比较,差异无统计学意义(P> 0. 05);术后4 d、7 d,2组患者的AIS失眠评分均比术后1 d有所降低,但观察组的降低幅度比对照组明显;且观察组拔管后10 min、20 min、的Ramsay镇静评分均明显高于对照组;术后不良反应发生率(8. 93%)也较低于对照组(23. 21%),组间比较差异有统计学意义(P <0. 05)。结论:右美托咪定对于胃肠手术全身麻醉患者具有良好的镇静效果,并能够改善术后睡眠情况,且不良反应较少,值得临床推广使用。

Effect of Dexmedetomidine-assisted Sedation on Sleep Function after General Anesthesia

Objective: To investigate the effect of dexmedetomidine assisted sedation on sleep function after general anesthesia. Methods: A total of 78 patients who underwent gastrointestinal surgery under general anesthesia in our hospital from December 2017 to December 2018 were selected as research objects,and randomly divided into control group and observation group,39 cases in each group.The control group was given propofol general anesthesia,while the observation group was given dexmedetomidine auxiliary general anesthesia on the basis of the control group.To observe and compare the AIS insomnia score,Ramsay sedation score at 10 min and 20 min after extubation,as well as the incidence of adverse reactions of the two groups at 1 d,4 d and 7 d after surgery. Results: One day after surgery,there was no statistically significant difference in AIS insomnia scores between the two groups( P >0.05).4 d and 7 d after surgery,AIS insomnia scores of both groups were slightly lower than that of the control group,but the decrease was more significant in the observation group than in the control group.Moreover,Ramsay sedation scores at 10 min and 20 min after extubation in the observation group were significantly higher than those in the control group.The incidence of postoperative adverse reactions(8.93%)was lower than that of the control group(23.21%),and the comparison between groups was statistically significant( P <0.05). Conclusion: Dexmedetomidine has a good sedative effect for patients under general anesthesia during gastrointestinal surgery,and can improve postoperative sleep,with few adverse reactions,which is worthy of clinical application.