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手参块茎化学成分研究Ⅱ
引用本文:李敏,郭顺星,王春兰,杨峻山,肖培根. 手参块茎化学成分研究Ⅱ[J]. 中国药学杂志, 2008, 43(6): 409-411
作者姓名:李敏  郭顺星  王春兰  杨峻山  肖培根
作者单位:中国医学科学院,中国协和医科大学药用植物研究所,北京,100094
摘    要: 目的研究手参(Gymnadenia conopsea)块茎的化学成分、方法采用各种柱色谱法进行分离纯化,运用理化性质和波谱法进行结构鉴定。结果从手参块茎乙醇提取物中得到11个化合物,分别为十六烷酸甘油三酯(Ⅰ)、十八烷酸(Ⅱ)、β-谷甾醇(Ⅲ)、胡萝卜苷(Ⅳ)、对-羟基苯甲醛(Ⅴ)、丁二酸(Ⅵ)、coelovirins B(Ⅶ)、gymnadesideⅠ(Ⅷ)、dactylorhin E(Ⅸ)、coelovi- rins F(Ⅹ)、coelovifins G(Ⅺ)。结论化合物Ⅰ,Ⅵ,Ⅶ,Ⅸ,Ⅹ,Ⅺ均为首次从手参属植物分得。

关 键 词:手参  化学成分  coelovirins
文章编号:1001-2494(2008)06-0409-04
收稿时间:2007-05-01;
修稿时间:2007-05-01

Studies on Chemical Constituents of the Tubers of Gymnadenia conopsea
LI Min,GUO Shun-xing,WANG Chun-lan,YANG Jun-shan,XIAO Pei-gen. Studies on Chemical Constituents of the Tubers of Gymnadenia conopsea[J]. Chinese Pharmaceutical Journal, 2008, 43(6): 409-411
Authors:LI Min  GUO Shun-xing  WANG Chun-lan  YANG Jun-shan  XIAO Pei-gen
Affiliation:Institute of Medical Plant Development,Chinese Academy of Medicinal Sciences and Peking Union Medical College,Beijing 100094,China
Abstract:OBJECTIVE To study chemical constituents of the tubers of Gymnadenia conopsea.METHODS The compounds were isolated by column chromatographic methods,their structures were elucidated on the basis of physical properties and spectral anal- ysis.RESULTS Eleven compounds were isolated from ethanol extract of this plant and identified as hexadecanoic triglyceride(Ⅰ), stearic acid(Ⅱ),β-sitosterol(Ⅲ),daucosterol(Ⅳ),p-hydroxybenzaldehyde(Ⅴ),succinic acid(Ⅵ),coelovirins D(Ⅶ),gymnadesideⅠ(Ⅷ),dactylorhin E(Ⅸ),coelovirins F(Ⅹ),coelovirins G(Ⅺ).CONCLUSION CompoundⅠ,Ⅵ,Ⅶ,Ⅸ,ⅩandⅪwere ob- tained from the plants of Gymnadenia R.Br for the first time.
Keywords:Gymnadenia conopsea')"   href="  #"  >Gymnadenia conopsea  chemical constituents  coelovirins
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