金钗石斛的化学成分和药理作用研究进展

目的 对金钗石斛的化学成分和药理作用进行总结分析。方法 通过查阅中国期刊全文数据库（CNKI）和万方数据库2000—2013年的相关文献,对金钗石斛已报道的化学成分和药理作用进行了研究分析,总结阶段性进展和研究热点,并分析其原因。结果 金钗石斛主要化学成分为生物碱、多糖、倍半萜类、菲类、联苄类等,石斛碱是其特征性成分,主要有抗白内障、兴奋肠管、免疫调节、降血糖、抗肿瘤、抗氧化、抗疲劳等作用。结论 目前金钗石斛的研究仍侧重于化学成分与药理作用的研究,将来研究的重点可能为作用机制的明确和一些保健品的研发。

Advances of Studies on Chemical Constituents and Pharmacological Effect of Dendrobium Nobile

OBJECTIVE To summarize the chemical components and pharmacological effect ofDendrobium nobile Lindl. METHODS Reviewed the related papers in Chinese Journal Full Text Database （CNKI） and Wanfang database during 2000-2013, the chemical components and pharmacological effects ofDendrobium nobile was analyzed, and then summarized the progress, focus of research, and causes. RESULTS The main chemical components of Dendrobium nobile Lindl included alkaloids, polysaccharide, sesquiterpene, phenanthrenes, bibenzyls etc. Dendrobium alkali was its characteristic components, the main pharmacological effects included anti-cataract, exciting bowel, immunoregulation, lowering blood sugar, anti-tumor, anti-oxidation, anti-fatigue, etc. CONCLUSION The research of Dendrobium nobile is still focused on the chemical constituents and pharmacological effect, the future research may focus on mechanism and research of health products.