Radiothérapie en conditions stéréotaxiques des gliomes de haut grade : une revue de la littérature |
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Authors: | J.-B. Clavier, J. Voirin, P. Kehrli,G. Noë l, |
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Affiliation: | a Département de radiothérapie, centre de lutte contre le cancer Paul-Strauss, 3, rue de la Porte-de-l’Hôpital, BP 42, 67065 Strasbourg cedex, France;b Service de neurochirurgie, hôpital de Hautepierre, avenue Molière, 67098 Strasbourg, France |
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Abstract: | The purpose of this literature systematic review was the use of stereotactic radiotherapy in glioma. Research was performed in Medline/PubMed and associated references found in published articles without publication date limit. The quality of series is variable and many biases can be evidenced. Only two randomized trials have been published using stereotactic radiotherapy for up-front treatment. There is a lack of evidence of survival advantages to use this treatment at the time of diagnosis or relapse. There is also insufficient evidence regarding the benefice/harms in the use of stereotactic fractionated radiation therapy for patients with glioma. No recommendations can be enounced. Stereotactic irradiation as boost in primary diagnosed glioma or relapsed tumour is not associated with survival improvement. For relapsed patients, treatment needs to be discussed according to the other treatment options. |
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Keywords: | Mots clé s: Gliome Radiochirurgie Radiothé rapie fractionné e en conditions sté ré otaxiques Evidence-based medicineGlioma Radiosurgery Stereotactic fractionated radiation therapy Evidence-based medicine |
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