Transient hyperthyroidism following L-asparaginase therapy for acute lymphoblastic leukemia |
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Authors: | Fadilah S A Faridah I Cheong S K |
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Affiliation: | Department of Haematology and Transplantation, MAKNA-HUKM Cancer Institute, Hospital Universiti Kebangsaan Malaysia, Jalan Tenteram, Cheras, 56000 Kuala Lumpur. |
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Abstract: | The effect of L-asparaginase on the thyroid gland has not been well documented. We report the first two cases of hyperthyroidism associated with thyroid nodule following L-asparaginase therapy for acute lymphoblastic leukemia (ALL). The thyroid function abnormalities were not severe, short-lived and did not require specific therapy. |
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