Synaptic plasticity to estrogen in the lateral septum of the adult male and female rats |
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| Authors: | Momoko Miyakawa Yasumasa Arai |
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| Affiliation: | Department of Anatomy, Juntendo University School of Medicine, Tokyo, Japan. |
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| Abstract: | There is no sex difference in the number of axodendritic synapses in the lateral septum of adult rats. However, the treatment of adult females with estradiol (E2) for 4 weeks increases significantly the number of synapses, whereas E2 treatment fails to increase the synaptic number in males, suggesting a possible sexually dimorphic synaptic response to estrogen. |
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| Keywords: | Synaptic plasticity Synaptogenesis Lateral septum Estrogen Adult rat |
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