恶性骨肿瘤局部化疗进展

局部化疗方法能够显著提升局部药物浓度、降低局部复发率,同时降低了全身化疗的毒副作用.近年来,开展了诸多骨肉瘤局部化疗方法,如动脉内灌注化疗、高温隔离灌注化疗、动脉介入治疗及栓塞、连续性血液滤过的血管介入区域性大剂量化疗等,取得了一些进展,局部治疗是一种骨肉瘤辅助治疗较为理想的方法.

Progress of local chemotherapy for the malignant bone tumors

Local chemotherapy was an efficient method for the malignant bone tumors,which can height markly the consistence of local drug and reduce the rate of local recur.In the same time,the method can also reduce the side-effection of CE regimen.For the past few years,considerable advances have been achieved in the fields of local therapy for malignant bone tumors,such as intra-arterial chemotherapeutic perfusion,hyperthermic isolatian limbperfusion,intra-arterial chemoembolization,HICCH et al.Local therapy would be an ideal methods for the treatment of osteosarcoma.