癔球症上食管括约肌运动功能及应激反应的研究

目的　探讨上食管括约肌 (UES)运动功能及其对应激的反应与癔球症的关系。方法　采用PolygrafHRTM食管测压系统对 2 2例癔球症患者进行UES运动功能测定 ,并进行冷加压试验 ,将 2 5例健康志愿者作为对照组。结果　癔球症组UES长度、静息压、松弛压及松弛率与正常对照组比较均无显著差异 (P >0 .0 5 )。咽与UES的协调性均较好。应激引起的UES压力增高癔球症组与对照组比较无明显不同 (P >0 .0 5 )。结论　癔球症患者的UES运动功能及其对应激的反应是正常的 ,UES功能状况可能与癔球症的发生无关

Study on upper esophageal sphincter motility and reactivity to stress in patients with globus sensation

Objective It is to discuss the relationship between upper esophageal sphincter (UES) motility and reactivity to stress and globus sensation.Methods UES motilities of twenty-two patients with globus sensation were mensurated with Polygraf HR TM Esophagus Manometry System. Twenty-five healthy volunteers were in control group. The cold pressor test was performed in the two groups.Results Compared with control group, the UES length, resting pressure, relax pressure and relax rate in globus sensation group had not significantly different (P>0.05). The correspondence of pharynx and UES in the two groups was good. The UES pressure rise stress-induced in globus sensation group had not significantly different compared with control group (P>0.05).Conclusion UES motility and its reactivity to stress are normal in patients with globus sensation. Maybe there is no relation between UES function status and globus sensation.