肝细胞癌螺旋CT表现特征与临床、病理关系的对照研究

目的　探讨肝细胞癌 (hepatocellularcarcinoma ,HCC)螺旋CT(spiralcomputedtomography ,SCT)增强表现特征与HCC多个临床、病理特征之间的关系。方法　对 5 0例 (男 3 9例 ,女 11例 )共 5 4个经手术病理证实且行SCT动、静脉双期增强扫描的HCC病灶进行回顾性分析 ,观察其SCT增强表现特征 ,包括包膜类型、强化类型、侵袭转移性、病灶大小和肝硬化等。记录HCC患者的临床和病理资料 ,如年龄、HBsAg、AFP值、肝硬化、瘤内有无坏死等情况。将SCT表现特征与上述指标进行对照分析。结果　SCT表现特征与HCC的病理表现具有相关性。与SCT显示的包膜类型有关的是病理分级 ,与强化类型有关的是病灶的大小和瘤内有无坏死 ,与SCT显示的侵袭转移性有关的是病灶的大小 ,与SCT显示的病灶大小有关的是AFP值 ,与SCT显示的肝硬化有关的是HBsAg和病灶的大小。结论　SCT各种的表现特征与HCC的某些临床和病理特征关系密切

Correlation Between Spiral CT Enhancement Features and Clinicopathologiacal Characteristics of Hapatocellular Carcinoma

Objective To study the correlation between the contrast enhancement features on spiral computed tomography (SCT) and different clinicopathological characteristics in hepatocellular carcinoma (HCC).Methods Fifty cases (54 lesions) of HCC proved pathologically and examined with enhancement dual-phase SCT scanning (arterial phase and portal vein phase) were included in this study. The SCT features and the clinical details about resection and pathological differentiation were recorded. All the features of SCT were compared with some clinical and histopathological characteristics of HCC.Results The features of SCT were correlated with pathological characteristics of HCC. The pseudocapsula patterns were related with Edmondson's grade, and the enhancement patterns were associated with the diameter of tumor and intratumoral necrosis. There was a significant correlation between the high infiltration and severity (intrahepatic daughter foci, tumor-emboli in portal veins, lymphatic metastasis) on the SCT images and the diameter of tumor. The same correlation was found between the diameter of tumor on the SCT images and AFP value, and also between hepatic cirrhosis on the SCT images and HBsAg, the diameter of tumor.Conclusion This research confirms that SCT features are correlated with some clinicopathological characteristics of HCC.