| 巨块型原发性肝癌TACE前后血清学指标及影像学变化的临床意义 |
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| 引用本文： | 郑里,张建新.巨块型原发性肝癌TACE前后血清学指标及影像学变化的临床意义[J].实用医技杂志,2008,15(33):4719-4721. |
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| 作者姓名： | 郑里 张建新 |
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| 作者单位： | 山西医科大学附属第一医院,山西太原,030001 |
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| 摘 要： | 目的:探讨巨块型原发性肝癌(PHC)患者介入治疗前后血清AFP、GGT和CA19-9水平变化及临床意义。方法:运用肝动脉栓塞化疗术(TACE)治疗巨块型原发性肝癌,TACE前后,对55例巨块型PHC患者应用RIA方法进行血清AFP、CA19-9含量检测,应用全自动生化仪检测GGT,比较观察分析各指标水平变化及治疗效果。结果:介入治疗前血清AFP、GGT含量显著高于正常参考值20ng/L和50U/L(P<0.01),介入治疗后1个月明显下降,术前术后差异显著,但仍显著高于正常,连续二、三次TACE后AFP、GGT水平逐渐下降。第一次介入治疗后6个月,影像学检查未转移者28例,发生肝内、外转移者27例,未转移者AFP、GGT趋于正常水平,而病灶增多或出现转移者AFP、CA19-9水平明显升高,与未转移组有显著差异(P<0.05)。结论:测定巨块型原发性肝癌患者血清中AFP、GGT和CA19-9水平的变化对评价TACE疗效、转移及预后均具有重要的临床价值。
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| 关 键 词： | 原发性肝癌 肝动脉栓塞化疗术 甲胎蛋白 谷酰转酞酶 糖类抗原CA19-9 |
Changes and Significance of Serum AFP,GGT,CA19-9 and Imaging in Patients with Giant Blocks of Primary Hepatocellular Carcinoma before and after TACE |
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| ZHENG Li,ZHANG Jian-xin.Changes and Significance of Serum AFP,GGT,CA19-9 and Imaging in Patients with Giant Blocks of Primary Hepatocellular Carcinoma before and after TACE[J].Journal of Practical Medical Techniques,2008,15(33):4719-4721. |
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| Authors: | ZHENG Li ZHANG Jian-xin |
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| Institution: | ZHENG Li; ZHANG Jian-xin(The Affiliated First Hospital of Shanxi Medical University; Taiyuan; Shanxi 030001; China); |
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| Abstract: | Objective To explore the giant block of primary hepatocellular carcinoma (PHC) before and after treatment intervention in patients with serum AFP, GGT and CA19-9 level changes and clinical significance. Methods The use of chemotherapy hepatic artery embolization (TACE) treatment of giant blocks of primary liver cancer, TACE before and after the giant block of 55 cases of patients with RAI method of serum AFP, CA19-9 in testing, application of automatic biochemical Detection of GGT, compared observe and anal... |
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| Keywords: | Primary hepatocellular carcinoma TACE AFP GGT CA19-9 |
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