| 人膀胱肿瘤DNA异常甲基化研究的临床意义 |
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| 引用本文： | 许闪闪.人膀胱肿瘤DNA异常甲基化研究的临床意义[J].国际肿瘤学杂志,2009,36(11). |
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| 作者姓名： | 许闪闪 |
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| 作者单位： | 同济大学附属第十人民医院检验科,上海,200072 |
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| 摘 要： | 膀胱肿瘤是我国最常见的泌尿外科肿瘤,无论其发病率或死亡率均占首位.DNA异常甲基化是肿瘤发生、发展过程中常见的表观遗传学改变,在膀胱肿瘤中扮演着重要角色.近年来,研究者对膀胱肿瘤DNA异常甲基化进行了大量的研究,为开辟膀胱肿瘤筛查、诊断和治疗的新途径奠定了实验基础.
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| 关 键 词： | 膀胱肿瘤 DNA甲基化 表观遗传学 |
Clinical significance of DNA aberrant methylation in bladder cancer |
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| XU Shan-shan.Clinical significance of DNA aberrant methylation in bladder cancer[J].Journal of International Oncology,2009,36(11). |
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| Authors: | XU Shan-shan |
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| Abstract: | Hie morbidity and mortality of bladder cancer are both the highest among urinary cancers in China. As a critical component of epigenetics, DNA abnormal methylation plays an important role during the occurrence and progression of bladder cancer. Recently, researchers focusing on the DNA methylation in bladder cancer have done much on it The results are of great clinical significance for screening,diagnosis and therapy of bladder cancer. |
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| Keywords: | Bladder neoplasms DNA methylation Epigenetics |
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