| 雷尼替丁加西沙必利与雷尼替丁治疗胃食管反流性疾病的疗效研究 |
| |
| 引用本文： | 杨丽 李朝英. 雷尼替丁加西沙必利与雷尼替丁治疗胃食管反流性疾病的疗效研究[J]. 中国内镜杂志, 1997, 3(4): 9-10 |
| |
| 作者姓名： | 杨丽 李朝英 |
| |
| 作者单位： | 华西医科大学附属第一医院 610041(杨丽，李朝英，吴俊超，王一平)，华西医科大学附属第一医院 610041(王维) |
| |
| 摘 要： | 将49例有胃食道反流症状、食道pH监测有病理性胃食道反流的患者随机分成两组(其中25例有内镜下食道炎)。一组用雷尼替丁(300mg,2次/d)加西沙必利(5mg,3次/d)(n=25);另一组单用雷尼替丁(300mg,2次/d)(n=24)治疗,疗程4周。结果显示:胃食道反流症状的好转率分别为88.00％、58.33％(P<0.05);食道pH值有效率分别为92.00％、54.17％(P<0.05);内镜下食道炎的愈合率分别为84.62％、50.00％(P>0.05)。以上结果表明:抑制胃酸分泌的药物与促动力剂合用是控制胃食道反流性疾病的最佳方法之一。
|
| 关 键 词： | 雷尼替丁 西沙必利 胃食管反流 消化道疾病 |
A COMPARISON OF THE EFFECTS OF RANITIDINE PLUS CISAPRIDE WITH RANITIDINE ON GASTROESOPHAGEAL REFLUX DISEASE |
| |
| Yang Li,Li Chaoying,Wu Juncao,et al.. A COMPARISON OF THE EFFECTS OF RANITIDINE PLUS CISAPRIDE WITH RANITIDINE ON GASTROESOPHAGEAL REFLUX DISEASE[J]. China Journal of Endoscopy, 1997, 3(4): 9-10 |
| |
| Authors: | Yang Li Li Chaoying Wu Juncao et al. |
| |
| Affiliation: | Yang Li,Li Chaoying,Wu Juncao,et al.First Affiliated Hospital,West China University of Medical Sciences,Chengdu,Sichuan 610041,P.R.China |
| |
| Abstract: | Forty nine patients with reflux symptoms and abnormal 24 hour pH monitoring were randomized into two groups, and 25 patients of them endoscopically confirmed reflux esophagitis. One group was treated with ramtidine (300mg/bid) plus cisapride (5mg/tid) (R C group, N = 25). The other group was treated with ranitidine (300mg/bid) (R group, N = 24). Both groups underwent treatment for four weeks. The symptom relief rate was 88. 00 % in the R C group and 58. 33 % in the R group (P < 0. 05). The effective rate of esophageal pi I monitoring was 92.00 %, 54.17% (P < 0. 05 ) . The healing rate of esophagitis was 84.62%, 50.00% (P<0.05). The results indicate that ranitidine plus cisapride is more effective than ranitidine in the treatment of gastroesophageal reflux disease. |
| |
| Keywords: | Ranitidine Cisapride Gastroesophageal reflux disease |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
