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血清骨特异性酸性磷酸酶的临床意义
引用本文:薛延,张海文,杨立红,王芊,郭三巧.血清骨特异性酸性磷酸酶的临床意义[J].中华内分泌代谢杂志,2003,19(6):466-467.
作者姓名:薛延  张海文  杨立红  王芊  郭三巧
作者单位:100035,北京积水潭医院生化研究室
摘    要:血清抗酒石酸酸性磷酸酶 5b(TRAP 5b)是反映骨吸收的一种标志物。本研究结果显示正常绝经后妇女血清TRAP 5b水平高于正常绝经前妇女 (P <0 .0 5 ) ,绝经后骨质疏松的妇女高于正常绝经后妇女 (P <0 .0 5 ) ,骨折、糖尿病、肾病等患者高于相应的对照者 (P <0 .0 5或P <0 .0 1)。

关 键 词:血清  骨特异性酸性磷酸酶  骨质疏松  抗酒石酸酸性磷酸酶5b  检测  骨折  糖尿病  肾病
修稿时间:2002年6月11日

Clinical significance of serum bone-specific acid phosphatase
XUE Yan,ZHANG Hai-wen,YANG Li-hong,WANG Qian,GUO San-qiao. Laboratory of Biochemistry,Jishuitan Hospital,Beijing.Clinical significance of serum bone-specific acid phosphatase[J].Chinese Journal of Endocrinology and Metabolism,2003,19(6):466-467.
Authors:XUE Yan  ZHANG Hai-wen  YANG Li-hong  WANG Qian  GUO San-qiao Laboratory of Biochemistry  Jishuitan Hospital  Beijing
Institution:XUE Yan,ZHANG Hai-wen,YANG Li-hong,WANG Qian,GUO San-qiao. Laboratory of Biochemistry,Jishuitan Hospital,Beijing 100035
Abstract:Serum tartrate-resistant acid phosphatase-5b (TRAP-5b) is a marker reflecting bone absorption. The results showed that serum TRAP-5b level was higher in postmenopausal than that in premenopausal normal women (P<0.05), higher in postmenopausal women with osteoporosis compared to normal postmenopausal women (P<0.05) and higher in the patients with bone fracture, diabetes and nephropathy than that in normal controls (P<0.05 or P<0.01).
Keywords:Tartrate-resistant acid phosphotase  Osteoporosis  Menopause  Bone fracture  Diabetes mellitus
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