| 厄贝沙坦对高血压病患者左心室肥厚的影响 |
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| 引用本文： | 肖智谦,陈平姬,陈永坚,吴英伟.厄贝沙坦对高血压病患者左心室肥厚的影响[J].医学文选,2005,24(3):317-318. |
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| 作者姓名： | 肖智谦 陈平姬 陈永坚 吴英伟 |
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| 作者单位： | 广西北海市合浦卫校附属医院 北海536100
(肖智谦，陈平姬，陈永坚)，广西北海市合浦卫校附属医院 北海536100(吴英伟) |
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| 摘 要： | 目的探讨厄贝沙坦对高血病(EH)患者左心室肥厚(LVH)的影响。方法采用自身前后对照的研究方法,应用厄贝沙坦治疗35例具有LVH的EH患者,疗程为180d,用超声心动图法分别检测其治疗前后能反映LVH程度的左心室舒张末期内径(LVDD)、左心室舒张末期室间隔厚度(LVDST)、左心室舒张末期后壁厚度(LVDPWT)和左室质量指数(LVMl)。结果治疗后的LVDD、LVDST、LVDPWT和LVMI均比治疗前的显著降低(均P<0.01)。结论二丁酰环磷腺苷钙可逆转EH患者LVH。
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| 关 键 词： | 厄贝沙坦 高血压病 左心室肥厚 超声心动图 |
Effects of Irbesartan on Left Ventricle Hypertrophy in Patients with Essential Hypertension |
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| XIAO Zhi-qian,CHEN Ping-ji,CHEN Yong-jian,WU Ying-wei.Effects of Irbesartan on Left Ventricle Hypertrophy in Patients with Essential Hypertension[J].Anthology of Medicine,2005,24(3):317-318. |
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| Authors: | XIAO Zhi-qian CHEN Ping-ji CHEN Yong-jian WU Ying-wei |
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| Abstract: | Objective To investigate the clinical effects of irbesartan on left ventricle hypertrophy (LVH) in patients with essential hypertension (EH).Methods It was a self-control study.35 cases with EH accompanied by LVH were treated with irbesartan.The period of treatment was 180 days.The levels of left ventricular diastolic diameter (LVDD),left ventricular diastolic septal thickness (LVDST),left ventricular diastolic posterior wall thickness (LVDPWT) and left ventricular mass index (LVMI) were measured before and after treatment respectively by echocardiography.Results After trecrtment,the levels of LVDD,LVDST,LVDPWT and LVMI were significantly lower than those before treatment (P<0.01).Conclusion Irbesartan can be used to revert LVH in patients with EH. |
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| Keywords: | Irbesartan Essential hypertension Left ventricle hypertrophy Echocardiography |
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