| HPLC法测定洛伐他汀含量的不确定度评估 |
| |
| 引用本文： | 宋更申,姜建国,高燕霞,张西如,闫凯,孙婷.HPLC法测定洛伐他汀含量的不确定度评估[J].中国当代医药,2010,17(13):48-49. |
| |
| 作者姓名： | 宋更申 姜建国 高燕霞 张西如 闫凯 孙婷 |
| |
| 作者单位： | 河北省药品检验所,河北石家庄,050011 |
| |
| 摘 要： | 目的：建立HPLC法测定洛伐他汀含量的不确定度评估的方法。方法：通过建立HPLC含量测定法的数学模型，找出影响不确定度的因素，并对各个不确定度的分量进行评估。结果：计算各分量的不确定度，由此计算合成不确定度，最终给出测定结果的扩展不确定度和置信水平。结论：建立的不确定度评估方法可用于HPLC法测定洛伐他汀含量的不确定度评估。
|
| 关 键 词： | 高效液相色谱法 洛伐他汀 不确定度 含量 |
Evaluation of uncertainty for the determination of iovastatin by HPLC |
| |
| Authors: | SONG Gengshen JIANG Jianguo GA O Yanxia ZHANG Xiru YAN Kai SUN Ting |
| |
| Institution: | (Hebei Provincial Institute for Drug Control,Shijiazhuang 050011,China) |
| |
| Abstract: | Objective：To establish a method of uncertaintY evaluation for the determination of Lovastatin by HPLC.Methods： The calculation formula for the uncertainty was deduced in the procedure of assy for lovastatin.Results：Each component of uncertainty was calculated by analyzing the variable parameters among the procedures.The combined uncertainty and confidence level were finally obtained by synthesizing the uncertainties of various component variables.Conclusion： This method is appropriate to be used in the uncertainty evaluation for the determination of Lovastatin by HPLC. |
| |
| Keywords: | HPLC Lovastatin Uncertainty Assay |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
