重型β珠蛋白生成障碍性贫血输血治疗现状

目的 了解重型β珠蛋白生成障碍性贫血(地贫)患者输血治疗现状.方法 2010-01-01/2010-06-30在作者医院定期输血的重型β地贫246例,男163例,女83例,分析患者的输血频次和输血量,检测输血前血红蛋白、网织红细胞及胆红素.结果 所有患者中,51例(20.73%)间隔不足21天输血1次,122例(49....

Survey on Beta Thalassemia Major Treatment by Blood Transfusion

Objective To investigate the status of beta thalassemia major treatment by blood transfusion.Methods A total of 246 patients（163 males,83 females） with beta thalassemia major treated by regular transfusion in our hospital From 2010-1-1 to 2010-6-30 were studied.The frequency and capacity of transfusion were analyzed,and the pre-transfusion hemoglobin,reticulocyte and bilirubin were tested.Results Among all the patients,the transfusion interval of 51 cases（20.73%） was less than 21 days,of 122 patients（49.59%） between 21 to 35 days,and of 73 cases（29.67%） more than 35 days.The average hemoglobin before transfusion was（76.10＋18.30）g/L,and the hemoglobin of 79 cases（32.11%） was more than 90g/L.Pre-transfusion reticulocyte,bilirubin and indirect bilirubin levels had negative correlation with hemoglobin level.Conclusion Most patients with beta thalassemia major accepted transfusion on schedule,but the blood transfusion effects were not good enough.Only a part of patients could fulfill high quantity and regular transfusion.